Protein Alignment Lmx1a and Hoxd13

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_032301.2
• Gene: Hoxd13 / 15433
• MGIID: 96205
• Length: 339
• Species: Mus musculus
• Alignment Length: 410
• Identity: 96/410 - (23%)
• Similarity: 136/410 - (33%)
• Gaps: 135/410 - (32%)

  Fly   119 GHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSP---AGTSVAT 180
            |.:|.|||||.:......     |..|..:.:..::..|||.|||:|||.||.|.   .|||..|
Mouse    20 GAAPASSSSSVAAPGQCR-----GFLSAPVFAGTHSGRAAAAAAAAAAAAAAASSFAYPGTSERT 79

  Fly   181 SQLGGAVAAAIAA----------AAAAAAAATTPTSTGPAATGSGNANGSG-------NGNGNGN 228
            .....:.::|:.|          ..|.|||||.....|..|.|.|...|:|       :|.|...
Mouse    80 GSSSSSSSSAVIATRPEAPVAKECPAPAAAATAAAPPGAPALGYGYHFGNGYYSCRMSHGVGLQQ 144

  Fly   229 GNGNGNGNGNGGGAATASAAAASKLSADCSGRTEV---------------------GHIKCEKNF 272
            .....:.:.:.||.........|.|::......||                     |:|.....|
Mouse   145 NALKSSPHASLGGFPVEKYMDVSGLASSSVPTNEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTF 209

  Fly   273 ELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSC 337
                |.|:..|:.::...|..:|   .||..:            ||::||..|.
Mouse   210 ----GSGEPRHEAYISMEGYQSW---TLANGW------------NSQVYCAKDQ----------- 244

  Fly   338 CHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQ 402
                 ||                            |..|.              |..|
Mouse   245 -----PQ----------------------------GSHFW--------------KSSF------- 255

  Fly   403 HCGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRV 467
             .|.|.|::.|:...|.||    :.|...|..|.|:.:..:..:....:..|..::..|.||.|.
Mouse   256 -PGDVALNQPDMCVYRRGR----KKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQ 315

  Fly   468 VQVWFQNQRAKMKKIQRKAK 487
            |.:||||:|.|.|||..|.|
Mouse   316 VTIWFQNRRVKDKKIVSKLK 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	12/51 (24%)
		LIM	333..388	CDD:295319	4/54 (7%)
		Homeobox	427..480	CDD:278475	16/52 (31%)
Hoxd13	NP_032301.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		7/12 (58%)
		HoxA13_N	<121..168	CDD:403486	8/46 (17%)
		Homeobox	275..329	CDD:395001	16/53 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910