DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and AgaP_AGAP005400

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_315409.2	Gene:	AgaP_AGAP005400 / 1276101	VectorBaseID:	AGAP005400	Length:	353	Species:	Anopheles gambiae

Alignment Length:	184	Identity:	42/184 - (22%)
Similarity:	68/184 - (36%)	Gaps:	52/184 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 CEGCGQKIHDRFLMNVG-------DANWHEQCLACCYCGMQLHHTCYV-RNSKLYCKMDYDRLFG 331
            |:|||:      :...|       ...|||:|..||.|...:....:: |..::||...|:..:.
Mosquito   173 CDGCGE------IFRAGTKKMEYKTRQWHEKCFCCCVCKTAIGTKSFIPREQEIYCAGCYEEKYA 231

  Fly   332 VKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRD---------GQLFCYR 387
            .:|..|...|....:..:..|   :|..||.|..|::.| .|::|..||         |:||..|
Mosquito   232 TRCIKCKKIITSGGVTYKNEP---WHRECFTCTHCQVSL-AGQRFTSRDEKPYCAECFGELFAKR 292

  Fly   388 ---------------------HDLEKEMFLAAAAAQHC---GFVGLDEEDLLRP 417
                                 .....:.|:.|......   ||: .||:|::.|
Mosquito   293 CTSCTKPITGIGGTRFISFEDRHWHNDCFICAMCKTSLVGRGFI-TDEQDVICP 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	15/59 (25%)
		LIM	333..388	CDD:295319	18/84 (21%)
		Homeobox	427..480	CDD:278475
AgaP_AGAP005400	XP_315409.2	LIM	51..105	CDD:295319
		LIM3_LIMPETin	108..166	CDD:188805
		LIM4_LIMPETin	173..226	CDD:188809	15/58 (26%)
		LIM5_LIMPETin	234..285	CDD:188814	14/54 (26%)
		LIM6_LIMPETin	293..348	CDD:188816	8/54 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910