Protein Alignment Lmx1a and PRIC1_ANOGA

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_308221.4
• Gene: PRIC1_ANOGA / 1269578
• VectorBaseID: AGAP007648
• Length: 923
• Species: Anopheles gambiae
• Alignment Length: 933
• Identity: 186/933 - (19%)
• Similarity: 254/933 - (27%)
• Gaps: 408/933 - (43%)

  Fly    76 HQQHQQQQHQQQQ-----QHPHQQHQQHQQQHA--------------------ASTTPVPINSC- 114
            |.|||....||||     .|.|..|..|...||                    ....|.|..|.
Mosquito    20 HPQHQLMLQQQQQADHSPHHHHHHHVHHATAHAYPYELGRSPLRSPQSPPLYSGKPPPPPPQSYH 84

  Fly   115 ----PTPTGHSPLSSSSSNSNH----------------NNNNNNNNGGS-------------SSN 146
                |....|.|:|.|.:.::.                ........|||             |.:
Mosquito    85 SYQQPPTAAHPPVSLSGAPTSMPGMMPGQQPPGMTLSLGGGGGGGGGGSAGDCFMLPPLQPQSPD 149

  Fly   147 NLHSACNTLTAAAVAAASAAAVAAP--SPAGTSVATSQ---LGGAVAAAI--------------- 191
            .|.:..|| ::.|..|.||.:|...  .|:..|:.:|.   ...|.|||:
Mosquito   150 GLSTVTNT-SSTATNAPSARSVYPQHHQPSYPSIGSSHHPFHSPASAAALIGPSMPQHAQQQQQH 213

  Fly   192 -------AAAAAAAAAATTPTSTGPAA----TGSGNANGSGNGNGNG---NGNGNGNGNGNGGGA 242
                   ::......|...|:|.|||:    .|.|...|.|.|.|.|   .|.|.|.|.|.|||.
Mosquito   214 QMQPHHYSSMHLLGPAGGPPSSVGPASMVGMMGPGGHGGGGVGGGAGGIAGGVGGGPGGGMGGGH 278

  Fly   243 ATA-----------------------------SAAAASKL------------------------- 253
            ..:                             ||....|:
Mosquito   279 NYSQSDDDSGCALEEYTWVPPGLRPDQVHLYFSAIPEDKVPYVNSIGERHRVRQLLQQLPPHDNE 343

  Fly   254 -----SADCSGRTEVGHIKCEKNFE--------------LCEGCGQ--------KIHDRFLMNVG 291
                 |.....|.|:.....::..|              :||.||:        ....||..|
Mosquito   344 VRYCHSLTDEERKELKLFSAQRKREALGRGTVKQITTTLICERCGECASSGDMMVFASRFEPN-- 406

  Fly   292 DANWHEQCLACCYCGMQLHHTCYV-RNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFV 355
             ..||..|.|||.|...|....|. |.::|||...:......:||:|...||..|..  ......
Mosquito   407 -TCWHPACFACCVCKELLVDLIYFHRENRLYCGRHHAETLKPRCSACDEIILADECT--EAEGRA 468

  Fly   356 FHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGF----VGLDEED--- 413
            :|:..|.|:.|...| .|:::::|||:.:|. |..:      |..|::|.:    :|:|:..
Mosquito   469 WHIKHFACFECDKQL-GGQRYIMRDGKPYCL-HCFD------AMFAEYCDYCSEPIGVDQGQMSH 525

  Fly   414 ---------------------LLRPRDGRRG------------PKRPRTILTSQQRKQFKASFDQ 445
                                 |.||...|||            |..|.... :.:..|...:..:
Mosquito   526 DGQHWHATDQCFACSTCRCSLLGRPFLPRRGEIYCSIACSKGEPPTPSDEY-AHRSSQPSHTAAR 589

  Fly   446 SPKPCRK-------------------------------------VREALAKDTG----------- 462
            ||:|.|.                                     .....|.|.|
Mosquito   590 SPEPLRSPERGTGRLSPPHTEHEVQSHEAASTVGSDRDHQLRSPASNGTATDNGTGTAGGGVGDS 654

  Fly   463 ---------------LSVRVVQVWFQNQRAKMKKIQ----------------RKAKQNGGSGGG- 495
                           |...:.|.| |::|...:.|.                ..|..||.:|||
Mosquito   655 NRHRIPHRQPLDLTDLGHSLEQHW-QSERTGSETISITTATATVRTQVTGPIAGANGNGPTGGGP 718

  Fly   496 ---------------SGSGRG---TGNSSAT-------------DDKD----------------- 512
                           :|||..   :|.:|.|             ||.|
Mosquito   719 ILTSSMPELNRCLAAAGSGESPSFSGTNSPTPMPIEDSVVANGGDDADEQNQNASDASHSIKEVR 783

  Fly   513 -TNDKED-----KCVKQELGGD------SSGYLGGLDSTFASQPLN-------------PNLPFS 552
             ..|.:|     |...|..||.      ||.|....|.....:..|             ...|.
Mosquito   784 FEGDFQDSLPRTKSYCQRNGGQRNRAAKSSSYASDDDELAEDETDNYHHRRHHHSHQREQQRPV- 847

  Fly   553 PDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHSNPHDMLANL 617
             ||..|.|..|.|||..|       ..|||     :..|.|:.||..|   :..|..|
Mosquito   848 -DDSDARSVCSTCSSSSS-------SADDD-----VYELPLRRTSYGG---TRIHYMP------- 889

  Fly   618 NNSLINPIDKLYLMQNSYFSSEH 640
            ||||.....:..|..:|..:.:|
Mosquito   890 NNSLACARKRKQLQTSSGVAGQH 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	20/60 (33%)
		LIM	333..388	CDD:295319	16/54 (30%)
		Homeobox	427..480	CDD:278475	14/115 (12%)
PRIC1_ANOGA	XP_308221.4	PET_Prickle	283..378	CDD:193602	7/94 (7%)
		LIM1_Prickle	384..442	CDD:188799	20/60 (33%)
		LIM2_Prickle	447..502	CDD:188802	17/58 (29%)
		LIM3_Prickle	507..565	CDD:188804	9/57 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910