DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and AgaP_AGAP012744

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_024667070.1	Gene:	AgaP_AGAP012744 / 1268798	VectorBaseID:	AGAP012744	Length:	240	Species:	Anopheles gambiae

Alignment Length:	156	Identity:	42/156 - (26%)
Similarity:	68/156 - (43%)	Gaps:	22/156 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 KCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHH-TCYVRNSKLYCKMDYDRLF 330
            :|::.||        .|:| ::|.....||.||..|..|..|... ..|....:.||:.|:..||
Mosquito    21 RCDEGFE--------PHER-IVNSNGQLWHTQCFVCAQCFRQFQDGIFYEFEGRKYCEKDFHILF 76

  Fly   331 GVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDL---EK 392
            ...|:.|.:.::.: ::.....|  :|..||.|..|.:||  .:...:|:.:..|  ||.   ||
Mosquito    77 APCCAKCNNFVIGR-VIKAMAAN--WHPQCFTCERCSIPL--ADSGFIRNQKPLC--HDCNRKEK 134

  Fly   393 EMFLAAAAAQHCGFVGLDEEDLLRPR 418
            |:.|.......|.  |:.::..||.|
Mosquito   135 EVGLGKLVCNKCH--GIIDDAPLRFR 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	14/52 (27%)
		LIM	333..388	CDD:295319	12/54 (22%)
		Homeobox	427..480	CDD:278475
AgaP_AGAP012744	XP_024667070.1	LIM1_PINCH	19..77	CDD:188717	18/64 (28%)
		LIM	80..130	CDD:295319	14/56 (25%)
		LIM3_PINCH	143..203	CDD:188719	5/18 (28%)
		LIM	209..>240	CDD:295319
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910