Protein Alignment Lmx1a and lmx1b.1

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_002937918.1
• Gene: lmx1b.1 / 100495130
• XenbaseID: XB-GENE-494750
• Length: 400
• Species: Xenopus tropicalis
• Alignment Length: 429
• Identity: 156/429 - (36%)
• Similarity: 218/429 - (50%)
• Gaps: 99/429 - (23%)

  Fly   244 TASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQ 308
            |.:|.....|.::|..:.            :||||.:.|.|||||.|.:|:|||:||.|..|...
 Frog    37 TGTATLGVLLGSECQHQA------------VCEGCQRPISDRFLMRVNEASWHEECLQCTVCQQP 89

  Fly   309 LHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKG 373
            |..:||.|:.||:||.||.:||..|||.|...|.|.|.|||.: ..|:||.||.|..|...|:||
 Frog    90 LTTSCYFRDRKLFCKQDYQQLFAAKCSGCMEKIAPTEFVMRAL-ECVYHLSCFCCCVCERQLRKG 153

  Fly   374 EQFMLRDGQLFCYRHDLEKEMFLAAAAA--QHCGFVGLDEEDLLRP-----------RDGR--RG 423
            ::|:|::|||.| :.|.|||..|.::.:  ........|||..::|           .||:  |.
 Frog   154 DEFVLKEGQLLC-KSDYEKEKDLLSSGSPDDSDSVKSDDEEGDVKPGKCHVNQGKGSDDGKDPRR 217

  Fly   424 PKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQ 488
            |||||||||:|||:.|||||:.|.||||||||.||.:|||||||||||||||||||||:.|:.:|
 Frog   218 PKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQ 282

  Fly   489 NGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGD-SSGYLGGLDSTFASQPLNP----- 547
                                       ::::...|.||.: .|..:.|:.:::|  ||.|
 Frog   283 ---------------------------QQEQQNSQRLGQEVMSSRMEGMMTSYA--PLAPPQQQI 318

  Fly   548 ---------NLPF----SPDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSS 599
                     ..||    :|...|.:..:.:.:..:      |..:|.|....||::..|.|:.
 Frog   319 VTMDQNSYSTDPFQQGLTPPQMPGDHMNPYGNDTI------FHDIDSDTSLTSLSDCFLASSE-- 375

  Fly   600 GNQHSHSHSNPHDMLANLNNSLINPIDKLYLMQNSYFSS 638
                          :.::...:.||||:||.||:|||:|
 Frog   376 --------------VTSMQARVGNPIDRLYSMQSSYFAS 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	28/51 (55%)
		LIM	333..388	CDD:295319	26/54 (48%)
		Homeobox	427..480	CDD:278475	43/52 (83%)
lmx1b.1	XP_002937918.1	LIM1_Lmx1b	56..108	CDD:188757	28/51 (55%)
		LIM2_Lmx1a_Lmx1b	115..169	CDD:188764	25/55 (45%)
		Homeobox	221..275	CDD:365835	44/53 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I8965
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323174at33208
OrthoFinder	1	1.000	-	-		FOG0001820
OrthoInspector	1	1.000	-	-		otm49088
Panther	1	1.100	-	-	O	PTHR24208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	1	1.000	-	-		X1182
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.050