Protein Alignment Lmx1a and nkx2-3

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_002937234.1
• Gene: nkx2-3 / 100486189
• XenbaseID: XB-GENE-852996
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 279
• Identity: 65/279 - (23%)
• Similarity: 97/279 - (34%)
• Gaps: 80/279 - (28%)

  Fly   377 MLRDGQLFCYRHDLEKEMFLAA-AAAQHCGFVGL----------------DEEDLLR-------- 416
            ||..|:...|....:|..||:| .||:..|.|||                :|||.||
 Frog    60 MLAAGERCVYAGGEDKLPFLSAMGAAEPHGDVGLSPDRYVALRDPKEEDEEEEDSLREGGNKSCF 124

  Fly   417 --------------PRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRV 467
                          .|..:|..::||.:.:..|..:.:..|.|........||.||....|:...
 Frog   125 LNKSPDGEGKLEDPDRPKQRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLANSLKLTSTQ 189

  Fly   468 VQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGY 532
            |::||||:|.|.|:.::......|:.......|........|.|       .|:     |.|..|
 Frog   190 VKIWFQNRRYKCKRQRQDKSLEMGTHHPPPPRRVAVPVLVRDGK-------PCI-----GGSQSY 242

  Fly   533 LGGLDSTFASQPLNPNLPFSPDDYPA-----------NSNDSFCS--SDLSLDGSNFDQLDDDAD 584
            ....:.|.:        |:|.:.|||           |.|.::.|  |:|...|:        :.
 Frog   243 NTAYNVTAS--------PYSYNSYPAYSYNNSPSYNTNYNCNYASIPSNLHNTGT--------SP 291

  Fly   585 SLSLNNLELQSTSSSGNQH 603
            .::|.||...|.|.....|
 Frog   292 FVNLGNLSQISNSPQPQTH 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319	4/10 (40%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
nkx2-3	XP_002937234.1	Homeobox	149..203	CDD:365835	17/53 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910