Protein Alignment Lmx1a and isl2

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001159513.1
• Gene: isl2 / 100306962
• XenbaseID: XB-GENE-487556
• Length: 333
• Species: Xenopus tropicalis
• Alignment Length: 387
• Identity: 114/387 - (29%)
• Similarity: 154/387 - (39%)
• Gaps: 96/387 - (24%)

  Fly   265 HIKCEKNFELCEGCGQKIHDRFLMNVG-DANWHEQCLACCYCGMQLHH--TCYVRNSKLYCKMDY 326
            |.|.:....:|.|||..|.|::::.|. |..||..||.|..|...|..  ||:||:.|.|||.||
 Frog    17 HPKKKAGLAVCVGCGSHILDQYILRVSPDLEWHAACLKCAECSQYLDENCTCFVRDGKTYCKRDY 81

  Fly   327 DRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLE 391
            .|||..:|..|...:...||||| :...|:|..||.|..|...|..||:..|||..|.|
 Frog    82 IRLFSARCPRCQGTLPRSELVMR-VGERVYHTDCFRCSVCSRRLLPGEEISLRDQDLLC------ 139

  Fly   392 KEMFLAAAAAQHCGFVGLDEEDLLRPRDGR-------RGPKRPRTILTSQQRKQFKASFDQSPKP 449
                    .|:|      :..|..||...|       ....|.||:|..:|....:..:..:|:|
 Frog   140 --------GAEH------NLSDSGRPSSLRSHIHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRP 190

  Fly   450 CRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTN 514
            ...::|.|.:.||||.||::|||||:|.|.||.....||                   ...:..|
 Frog   191 DALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQ-------------------LQQQQLN 236

  Fly   515 DKEDKCVKQELGGDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANS--------------NDSFC 565
            ||..              |.||..|    |:....|...|.....|              :|...
 Frog   237 DKTS--------------LQGLTGT----PMVAGSPIRHDSAVQGSAVEVQTYQPPWKALSDFAL 283

  Fly   566 SSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHSNPHDMLANLNNSLI-NPID 626
            .||  ||...|.||...::|.||.|       |||:..:...|    .|.:..||:: :|::
 Frog   284 QSD--LDQPAFQQLVSFSESGSLGN-------SSGSDIASLSS----QLPDTPNSMVPSPVE 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	24/54 (44%)
		LIM	333..388	CDD:295319	21/54 (39%)
		Homeobox	427..480	CDD:278475	21/52 (40%)
isl2	NP_001159513.1	LIM1_Isl	27..81	CDD:188752	23/53 (43%)
		LIM2_Isl	89..143	CDD:188760	22/68 (32%)
		HOX	165..221	CDD:197696	22/55 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910