Protein Alignment CG4328 and lhx2b

DIOPT Version :10

• Sequence 1: NP_648567.2
• Gene: CG4328 / 39405
• FlyBaseID: FBgn0036274
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001035099.3
• Gene: lhx2b / 791744
• ZFINID: ZDB-GENE-051220-1
• Length: 427
• Species: Danio rerio
• Alignment Length: 460
• Identity: 114/460 - (24%)
• Similarity: 180/460 - (39%)
• Gaps: 115/460 - (25%)

  Fly    95 SNSSSSSSTNSSSNMAINKQPMGMGPGTGTGMGTGTGHGPGPPNHTHCNRITLGECSLNGMDGFA 159
            |:.::..|.:|::.|..:            |:..|..||            .:.|....|....|
Zfish    18 SDGNTCYSVSSAATMLFH------------GLPGGEMHG------------VMEEMERRGKSDSA 58

  Fly   160 TPAAPPSASNTPQAPLGMASNSGMGMELGLAMASPQLSQCAHCCQPICDRYIMRVVENSFHEGCL 224
            |.:   ||.:..:....|.|.||           .:::.||.|...|.|||.:..|:..:|..||
Zfish    59 TIS---SAIDMGETETNMPSISG-----------DRVALCAGCGGKISDRYYLLAVDKQWHMRCL 109

  Fly   225 KCTACSLHLVH--SCYAREGKLYCRVDYERLYIRNHCLGCGLKIAADELVMRCHENVFHLKCFAC 287
            ||..|.|:|..  :|::::|.:||:.||.|.:....|..|.|.|:|.|:|||..:.|:||.||.|
Zfish   110 KCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTC 174

  Fly   288 VVCGALLKKGEQYVVKQGQLFCRFDYEKEVEMLQG---YDFYGDELFPPKLDGRRGP-------- 341
            ..|..:|..|:.:.:|...::||..:|   .::||   ..|...::.|.|.....||
Zfish   175 TTCNKMLTTGDHFGMKDSLVYCRLHFE---TLIQGDFPTHFNHTDVAPNKGLSSTGPLGLSYYNG 236

  Fly   342 --------------------------------------------------KRPRTILNTQQRRAF 356
                                                              ||.||.....|.|..
Zfish   237 VNTVQKGRPRKRKSPGPGADLAAYNAALSCNENDGDPMDRDSQYSSSQKTKRMRTSFKHHQLRTM 301

  Fly   357 KASFEVSPKPCRKVRENLAKDTGLSLRIVQVWFQNQRAKVKKIQKKAKQEPPSKGASDSQDSQES 421
            |:.|.::..|..|..:.||:.|||:.|::||||||.|||.::...:.:.....| |||..:....
Zfish   302 KSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDK-ASDGSNLAGG 365

  Fly   422 LDSSLATKIKDEAHSDSESQLESPYSTTSDGLTRMRC-TIKDEQEQVPFNCMETNKENCNKNSEP 485
            ..|..|::|.:.:.|.|.:      .||...||.... |:......||.:   .:...|...|:.
Zfish   366 TPSGPASEISNASMSPSST------PTTLTDLTNPTMPTVTSVLTSVPGS---LDVHECRSPSQS 421

  Fly   486 ILNTI 490
            .|.::
Zfish   422 TLTSL 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4328	NP_648567.2	LIM1_Lmx1b	199..251	CDD:188757	21/53 (40%)
		LIM	259..313	CDD:413332	21/53 (40%)
		COG5576	<332..439	CDD:227863	37/164 (23%)
		HOX	341..393	CDD:197696	23/109 (21%)
lhx2b	NP_001035099.3	LIM1_Lhx2	74..137	CDD:188853	23/73 (32%)
		LIM2_Lhx2_Lhx9	142..200	CDD:188763	21/57 (37%)
		COG5576	<267..389	CDD:227863	36/128 (28%)
		Homeodomain	287..343	CDD:459649	25/55 (45%)