Protein Alignment CG4328 and Lhx4

DIOPT Version :10

• Sequence 1: NP_648567.2
• Gene: CG4328 / 39405
• FlyBaseID: FBgn0036274
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001101818.2
• Gene: Lhx4 / 360858
• RGDID: 1308044
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 97/279 - (34%)
• Similarity: 148/279 - (53%)
• Gaps: 32/279 - (11%)

  Fly   182 GMGMELGLAMASPQLSQCAHCCQPICDRYIMRVVENSFHEGCLKCTACSLHLVHSCYAREGKLYC 246
            |:...||:.|  .|:.|||.|.|.|.|::|::|::..:|..||||..|.:.|...|::|.|.:||
  Rat    15 GLPEMLGVPM--QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYC 77

  Fly   247 RVDYERLYIRNHCLGCGLKIAADELVMRCHENVFHLKCFACVVCGALLKKGEQ-YVVKQGQLFCR 310
            :.|:.:.: ...|..|...|...::|.:..:.|:||.||||::|...|..|:: |:::.|:|.|:
  Rat    78 KEDFFKRF-GTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCK 141

  Fly   311 FDYEKEVEMLQGYDFYGDELFPPKLDGRRGPKRPRTILNTQQRRAFKASFEVSPKPCRKVRENLA 375
            .|||...:        .|       |...|.|||||.:..:|....|.:::.||||.|.|||.|:
  Rat   142 EDYETAKQ--------ND-------DSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLS 191

  Fly   376 KDTGLSLRIVQVWFQNQRAKVKKIQKKA---------KQEPPSKGASDSQDSQESLDSSLATKIK 431
            .:|||.:|:|||||||:|||.|:::|.|         |....|:|.|    .||...|:....:.
  Rat   192 SETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGGS----KQEKESSAEDCGVS 252

  Fly   432 DEAHSDSESQLESPYSTTS 450
            |...|..|.|:.|....|:
  Rat   253 DSELSFREDQILSELGHTN 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4328	NP_648567.2	LIM1_Lmx1b	199..251	CDD:188757	21/51 (41%)
		LIM	259..313	CDD:413332	18/54 (33%)
		COG5576	<332..439	CDD:227863	44/115 (38%)
		HOX	341..393	CDD:197696	27/51 (53%)
Lhx4	NP_001101818.2	LIM1_Lhx4	30..81	CDD:188852	20/50 (40%)
		LIM2_Lhx3_Lhx4	89..144	CDD:188762	18/54 (33%)
		Homeodomain	158..214	CDD:459649	30/55 (55%)