Protein Alignment CG4328 and Lmx1a

DIOPT Version :10

• Sequence 1: NP_648567.2
• Gene: CG4328 / 39405
• FlyBaseID: FBgn0036274
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_061498757.1
• Gene: Lmx1a / 3289904
• VectorBaseID: AGAMI1_004173
• Length: 491
• Species: Anopheles gambiae
• Alignment Length: 492
• Identity: 163/492 - (33%)
• Similarity: 220/492 - (44%)
• Gaps: 140/492 - (28%)

  Fly   164 PPSASNTPQAPLGMASNSGM--GME----LGLAMASPQLSQCAHCCQPICDRYIMRVVENSF-HE 221
            ||:|   |.|...:..|:.|  |.|    :|...:......|..|.|.|.|||.|::..:.| ||
Mosquito    15 PPAA---PNADTNLKDNNSMLDGNERADIVGTIKSEKTQEICEGCGQKIKDRYFMKLSPDQFWHE 76

  Fly   222 GCLKCTACSLHLVHSCYAREGKLYCRVDYERLY---------IRNH----------------CLG 261
            .||.|..|.:.|..:||.:..|:||:.||.|::         .::|                |.|
Mosquito    77 QCLLCCICRIQLSQTCYTKNTKVYCKDDYYRIFGVSSVHQQNQQHHQQHGQQHGQQQQHQRDCYG 141

  Fly   262 CGLKIAADELVMRCHENVFHLKCFACVVCGALLKKGEQYVVKQGQLFCRFDYEKEVEMLQGYDFY 326
            ||.:||..|:|||....|:||.||.|..|...|:|||.:.::.|:|.|:.|.||        |||
Mosquito   142 CGERIAPSEMVMRAKHLVYHLHCFLCYTCNRPLQKGEPFSIRAGKLICQHDLEK--------DFY 198

  Fly   327 GDEL----------------------------FPPKL------------------DGRRGPKRPR 345
            |...                            .||..                  ||||||||||
Mosquito   199 GSAAAAAAAAAAAAAAAMHHHHGGAGAGLGPHLPPAAHLYGDGDDYLLDDGLRTRDGRRGPKRPR 263

  Fly   346 TILNTQQRRAFKASFEVSPKPCRKVRENLAKDTGLSLRIVQVWFQNQRAKVKKIQKKAKQEPPSK 410
            |||.:.|||.|||||:|||||||||||.||||||||:|:|||||||||||:|||.:|:|..  :.
Mosquito   264 TILTSAQRRQFKASFDVSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKISRKSKAN--AN 326

  Fly   411 GASDSQDSQESLDSSLATKIKDEAHSDSESQ---LESPYSTTS--------------DGLTRMRC 458
            ||:|.:.:....:..   .||.|:.|...|.   |:|.||::|              |......|
Mosquito   327 GATDGEKNHSDKEDK---SIKLESPSSDHSHYLGLDSSYSSSSQPLNPNLPYSPDFPDNSDASLC 388

  Fly   459 TIKDEQEQVPFNCMETNKENC---NKNSEPIL--NTIL--------------GLSYATFQQL--- 501
            :.....::...|..|...:..   |.:.:|.|  |.::              ||.....|||
Mosquito   389 SSDISLDESFDNVDEATSDTMSLQNLDLQPNLHSNGVMGGGGGGQGPTCSGPGLHGGGPQQLVNH 453

  Fly   502 ----MGPFAQTPM---INPIDRLYSMQSSYFRPEELQ 531
                :|....:.|   |..||:||.||:|||...:::
Mosquito   454 NNNTIGSMMASNMAGSITHIDKLYLMQNSYFNSAQIE 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4328	NP_648567.2	LIM1_Lmx1b	199..251	CDD:188757	22/52 (42%)
		LIM	259..313	CDD:413332	24/53 (45%)
		COG5576	<332..439	CDD:227863	66/124 (53%)
		HOX	341..393	CDD:197696	43/51 (84%)
Lmx1a	XP_061498757.1	None