Protein Alignment CG4328 and isl1a

DIOPT Version :10

• Sequence 1: NP_648567.2
• Gene: CG4328 / 39405
• FlyBaseID: FBgn0036274
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_571037.1
• Gene: isl1a / 30147
• ZFINID: ZDB-GENE-980526-112
• Length: 349
• Species: Danio rerio
• Alignment Length: 294
• Identity: 91/294 - (30%)
• Similarity: 141/294 - (47%)
• Gaps: 49/294 - (16%)

  Fly   196 LSQCAHCCQPICDRYIMRVVEN-SFHEGCLKCTACSLHLVHS--CYAREGKLYCRVDYERLY-IR 256
            :|.|..|...|.|:||:||..: .:|..||||..|:.:|..|  |:.|:||.||:.||.||| |:
Zfish    14 ISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIK 78

  Fly   257 NHCLGCGLKIAADELVMRCHENVFHLKCFACVVCGALLKKGEQYVVKQGQLFCRFDYEKEVEMLQ 321
              |..|.:..:.::.|||....|:|::||.||.|...|..|:::.:::..||||.|::.......
Zfish    79 --CAKCNIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERATM 141

  Fly   322 GYDFYGDELFP-----------PKLDGRRGPKRP------------RTILNTQQRRAFKASFEVS 363
            |   .||.|.|           ..:..|:...||            ||:||.:|....:..:..:
Zfish   142 G---AGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYNAN 203

  Fly   364 PKPCRKVRENLAKDTGLSLRIVQVWFQNQRAKVKK---IQKKAKQEPPS--------KGASDSQD 417
            |:|...::|.|.:.||||.|:::|||||:|.|.||   :.|:.:|:.|:        .|......
Zfish   204 PRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQPNDKTNIQGMTGTPMVAT 268

  Fly   418 SQESLDSSLATKIKDEAHSDSESQLESPYSTTSD 451
            |.|..|..|      :|:.......:.|:...||
Zfish   269 SPERHDGGL------QANQVEVQSYQPPWKVLSD 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4328	NP_648567.2	LIM1_Lmx1b	199..251	CDD:188757	23/54 (43%)
		LIM	259..313	CDD:413332	18/53 (34%)
		COG5576	<332..439	CDD:227863	36/140 (26%)
		HOX	341..393	CDD:197696	21/63 (33%)
isl1a	NP_571037.1	LIM1_Isl	17..71	CDD:188752	22/53 (42%)
		LIM2_Isl	79..133	CDD:188760	18/53 (34%)
		HOX	181..237	CDD:197696	21/55 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..349