Protein Alignment CG4328 and Lmx1a

DIOPT Version :9

• Sequence 1: NP_648567.2
• Gene: CG4328 / 39405
• FlyBaseID: FBgn0036274
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001099437.2
• Gene: Lmx1a / 289201
• RGDID: 1304784
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 426
• Identity: 160/426 - (37%)
• Similarity: 221/426 - (51%)
• Gaps: 102/426 - (23%)

  Fly   155 MDGFATPAAPPSASNTPQAPLGMASNSGMGMELGLAMASPQLSQCAHCCQPICDRYIMRVVENSF 219
            :||........||..|      .||.|.:   ||.|: ||: |.|..|.:.|.||:::|:.::.:
  Rat     2 LDGLKMEENFQSAIET------SASFSSL---LGRAV-SPK-SVCEGCQRVISDRFLLRLNDSFW 55

  Fly   220 HEGCLKCTACSLHLVHSCYAREGKLYCRVDYERLYIRNHCLGCGLKIAADELVMRCHENVFHLKC 284
            ||.|::|.:|...|..:|:.|:.||||:..||:|:... |.||...||.:|.|||..::|:||.|
  Rat    56 HEQCVQCASCKEPLETTCFYRDKKLYCKYHYEKLFAVK-CGGCFEAIAPNEFVMRAQKSVYHLSC 119

  Fly   285 FACVVCGALLKKGEQYVVKQGQLFCRFDYEKEVEMLQGYDFYGDELFPPKL-------------- 335
            |.|.||...|:||:::|:|:|||.|:.|||||.|:|        .|..|..
  Rat   120 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELL--------SLVSPAASDSGKSDDEESLCK 176

  Fly   336 -----------DGR--RGPKRPRTILNTQQRRAFKASFEVSPKPCRKVRENLAKDTGLSLRIVQV 387
                       ||:  :.||||||||.||||||||||||||.||||||||.||.:||||:|:|||
  Rat   177 SAHGAGKGASEDGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQV 241

  Fly   388 WFQNQRAKVKKIQKKAKQEPPSKGASDSQDSQESLDSSLATKIKDEAHSDSESQLESPYST---- 448
            ||||||||:||:.::.:|:     ..|.|::|..  ||..|.....|..:.   :.:||:|
  Rat   242 WFQNQRAKMKKLARRQQQQ-----QQDQQNTQRL--SSAQTNGSGNAGMEG---IMNPYTTLPTP 296

  Fly   449 -----------TSD----GLTRMRCTIKDEQEQVPFNCMETNKENCNKNSEPILNTI-------- 490
                       .||    |||         ..|:|.:.|..      ..:||:.:.:
  Rat   297 QQLLAIEQSVYNSDPFRQGLT---------PPQMPGDHMHP------YGAEPLFHDLDSDDTSLS 346

  Fly   491 -LGLSYATFQQLMGPFAQTPMINPIDRLYSMQSSYF 525
             ||..:....: .||. |:.:.||||.|||||:|||
  Rat   347 NLGDCFLATSE-AGPL-QSRVGNPIDHLYSMQNSYF 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4328	NP_648567.2	LIM1_Lmx1b	199..251	CDD:188757	18/51 (35%)
		LIM	259..313	CDD:295319	26/53 (49%)
		COG5576	<332..439	CDD:227863	61/133 (46%)
		HOX	341..393	CDD:197696	44/51 (86%)
Lmx1a	NP_001099437.2	LIM1_Lmx1a	35..86	CDD:188756	18/50 (36%)
		LIM2_Lmx1a_Lmx1b	94..148	CDD:188764	26/53 (49%)
		Homeobox	198..252	CDD:395001	45/53 (85%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6686
eggNOG	1	0.900	-	-		E33208_3BAC6
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323174at33208
OrthoFinder	1	1.000	-	-		FOG0001820
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105498
Panther	1	1.100	-	-	O	PTHR24208
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1182
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.780