DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4328 and phx1

DIOPT Version :9

Sequence 1:	NP_648567.2	Gene:	CG4328 / 39405	FlyBaseID:	FBgn0036274	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_593776.1	Gene:	phx1 / 2542405	PomBaseID:	SPAC32A11.03c	Length:	942	Species:	Schizosaccharomyces pombe

Alignment Length:	194	Identity:	50/194 - (25%)
Similarity:	79/194 - (40%)	Gaps:	26/194 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 PKRPRTILNTQQRRAFKASFEVSPKPCRKVRENLAKDTGLSLRIVQVWFQNQRAKVKKIQKKAKQ 405
            ||..:..|...|.......|.....|...:||.:.::..:..|.|.:||||:|||.|.|.:  :|
pombe   166 PKSKKQRLTADQLAYLLREFSKDTNPPPAIREKIGRELNIPERSVTIWFQNRRAKSKLISR--RQ 228

  Fly   406 EPPSKGASDSQDSQESLDSSLATKIKDEAHSDSESQLESPYSTTSDGLTRMR---------CTIK 461
            |...:.....|...:||:..::.....|..|.|.:   |||   ..|:...|         .|.|
pombe   229 EEERQRILREQRELDSLNQKVSQAFAHEVLSTSPT---SPY---VGGIAANRQYANTLLPKPTRK 287

  Fly   462 DEQEQVPFNCMETNKENCNKNSE-PILNTILGLSYATFQQLMGPFAQTPMINPIDRLYSMQSSY 524
            .....:....|:::.|.|...|: ||..::    .:|:...:.|.| .|:.:  .|.|| .|||
pombe   288 TGNFYMKSGPMQSSMEPCIAESDIPIRQSL----SSTYYNSLSPNA-VPVSS--QRKYS-ASSY 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4328	NP_648567.2	LIM1_Lmx1b	199..251	CDD:188757
		LIM	259..313	CDD:295319
		COG5576	<332..439	CDD:227863	26/97 (27%)
		HOX	341..393	CDD:197696	14/51 (27%)
phx1	NP_593776.1	COG5576	116..272	CDD:227863	31/113 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000