DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4328 and Hoxa7

DIOPT Version :9

Sequence 1:NP_648567.2 Gene:CG4328 / 39405 FlyBaseID:FBgn0036274 Length:544 Species:Drosophila melanogaster
Sequence 2:NP_034585.1 Gene:Hoxa7 / 15404 MGIID:96179 Length:229 Species:Mus musculus


Alignment Length:375 Identity:77/375 - (20%)
Similarity:117/375 - (31%) Gaps:161/375 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 SVSRTVNGSCSNHNSSNSSSSSSTNSSSNMAINKQPMGMGPGTGTGMGTGTGHGPGPPNHTHCNR 144
            |.|..||...|.:.:..|...::..:|.:.|.|.|..|.|||.|....|    .||..|      
Mouse     2 SSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGPGAGAFAST----VPGLYN------ 56

  Fly   145 ITLGECSLNGMDGFATPAAPPSASNTP--QAPLGMASNSGMGME-LGLAMAS-----PQLSQCAH 201
                                   .|:|  |:|  .||..|:|.: ..|..||     |.|  |:.
Mouse    57 -----------------------VNSPLYQSP--FASGYGLGADAYNLPCASYDQNIPGL--CSD 94

  Fly   202 CCQPICDRYIMRVVENSFHEGCLKCTACSLHLVHSCYAREGKLYCRVDYE-RLY--IRNHCLGCG 263
            ..:..||:                             |.||.|:...:.. |:|  :|:      
Mouse    95 LAKGACDK-----------------------------ADEGVLHGPAEASFRIYPWMRS------ 124

  Fly   264 LKIAADELVMRCHENVFHLKCFACVVCGALLKKGEQYVVKQGQLFCRFDYEKEVEMLQGYDFYGD 328
                                      .|...|:|.|...:...|    :.|||        |:.:
Mouse   125 --------------------------SGPDRKRGRQTYTRYQTL----ELEKE--------FHFN 151

  Fly   329 ELFPPKLDGRRGPKRPRTILNTQQRRAFKASFEVSPKPCRKVRENLAKDTGLSLRIVQVWFQNQR 393
            ...                  |::||     .|::...|            |:.|.:::||||:|
Mouse   152 RYL------------------TRRRR-----IEIAHALC------------LTERQIKIWFQNRR 181

  Fly   394 AKVKKIQKKAKQEPPSKGASDSQDSQESLDSSLATKIKDEAHSDSESQLE 443
            .|.||..|...|.|    .:..:|:..|: |:.|.|..:|...:.|.:.|
Mouse   182 MKWKKEHKDESQAP----TAAPEDAVPSV-STAADKADEEEEEEEEEEEE 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4328NP_648567.2 LIM1_Lmx1b 199..251 CDD:188757 7/51 (14%)
LIM 259..313 CDD:295319 5/53 (9%)
COG5576 <332..439 CDD:227863 24/106 (23%)
HOX 341..393 CDD:197696 11/51 (22%)
Hoxa7NP_034585.1 Antp-type hexapeptide 118..123 1/4 (25%)
Homeobox 133..185 CDD:278475 19/98 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 186..229 12/46 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3844
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

Return to query results.
Submit another query.