Protein Alignment INPP5E and INP52

DIOPT Version :9

• Sequence 1: NP_001261753.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_014293.1
• Gene: INP52 / 855618
• SGDID: S000005050
• Length: 1183
• Species: Saccharomyces cerevisiae
• Alignment Length: 353
• Identity: 109/353 - (30%)
• Similarity: 165/353 - (46%)
• Gaps: 72/353 - (20%)

  Fly   384 RVLPQKE-------ITVFVGTWNMNGHSPPKQLNDFVLPANVEHVPDIVVMGTQE---------- 431
            |:|..:|       |.:||||:|:||:|....|:.::.|...:..||:||:|.||
Yeast   577 RLLESEEKFTTHSNINLFVGTFNVNGNSRRADLSKWLFPIGDKFKPDVVVLGLQEVIELTAGSIL 641

  Fly   432 ---STPDRFEWEVTIQETLG---PSHVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASMSVRTGS 490
               .|...| ||..:.:.|.   ..::|.....:.:|.:..:.|.|..:  ::.|....:.:||.
Yeast   642 NADYTKSSF-WETMVTDCLNQYEEKYLLLRVEQMSSLLILFFARSDRAY--NIKEVGGSTKKTGF 703

  Fly   491 AFRT--KGAVAISFCLFGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLPRNLPNQRHKNKDV 553
            ...|  ||||||.|....||..||.:||:|....:.||.:|...|...:..||:.....|
Yeast   704 GGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHH----- 763

  Fly   554 TQNFDNVFWCGDLNFRLGEPREKLLEWIQNTKFPLPSHLPHGY----MHTDQLTSVLADGAAFRG 614
                |::||.||||:|:....:::...::..|        .||    :..||||..:.:|..|:|
Yeast   764 ----DSLFWLGDLNYRITLTNDEVRRELRAQK--------DGYIDRLLQYDQLTQEINEGVVFQG 816

  Fly   615 FMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQGLVIRRQTLVPGVSTPTQPHV 679
            |.|..:.|.||||||.|:.|:|||.|.|.|::||||:||          .:.|.|
Yeast   817 FKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYK----------GENLHP---------- 861

  Fly   680 QCLLYDSVPSITTSDHKPVWALFRTLIR 707
              |.|...| :..||||||:|.:|..::
Yeast   862 --LAYSDAP-LKISDHKPVYAAYRANVK 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_001261753.1	EEP	387..703	CDD:321002	106/344 (31%)
INP52	NP_014293.1	COG5329	1..628	CDD:227637	18/50 (36%)
		COG5411	564..1052	CDD:227698	109/353 (31%)
		Aim21	<978..1166	CDD:371558

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810