Protein Alignment INPP5E and INP54

DIOPT Version :9

• Sequence 1: NP_001261753.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_014576.1
• Gene: INP54 / 854089
• SGDID: S000005426
• Length: 384
• Species: Saccharomyces cerevisiae
• Alignment Length: 383
• Identity: 94/383 - (24%)
• Similarity: 146/383 - (38%)
• Gaps: 116/383 - (30%)

  Fly   393 VFVGTWNM-------NGHSPPKQL----NDFVLPANVEHVPDIVVMGTQESTP------------ 434
            |.|.|:|.       |..:..|||    :|.:....::   |:.|:|.||..|
Yeast     8 VSVTTFNCGKEFPVENSKAIVKQLLFPYDDGISQLELQ---DLYVLGFQEVVPIWQGSFPAVNRD 69

  Fly   435 --DRFEWEVT------IQETLG-PSHVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASMSVRTGS 490
              ||......      :..|.| ..:......:||.:.:.|....:.:   .|.:|  :..|.|.
Yeast    70 LIDRITTTAVNCLNEKVSATQGDEQYSCLGVNSLGAITIIVLYNNNAL---KVKDD--ILKRNGK 129

  Fly   491 A--FRT--KGAVAISFCLFGTS------MLFVTSHLTAHQ--QKVKERVSDVKRIINALDLPRNL 543
            .  |.|  ||...|||.:....      ..::.:||.|::  ....:|:.|.|||::.:
Yeast   130 CGWFGTHLKGGTLISFQMTRNGEENWERFSYICAHLNANEGVNNRNQRIDDYKRIMSEV------ 188

  Fly   544 PNQRHKNKDVTQNFDNVFWCGDLNFRLGEPREKLLEWIQNTKFPLPSHLPHGYMHTDQLTSVL-- 606
                 .:.:|.:: |:.|:.||||||           :.:|..|..:     |..|..|..:|
Yeast   189 -----CDSEVAKS-DHFFFLGDLNFR-----------VTSTYDPTTN-----YSSTTTLRRLLEN 231

  Fly   607 ----------ADGAAFRGFMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQGLV 661
                      .|....:||.|..||||||||:....:  :|.:.:|.|::.||||||
Yeast   232 HEELNLLRKGEDEPLCKGFQELKITFPPTYKFKLFEK--ETYNTKRIPSWCDRILYK-------- 286

  Fly   662 IRRQTLVPGVSTPTQPHVQCLLYDSVP---SITTSDHKPVWALFRTLIRAGTDAIPLA 716
                    ..:.||  ..|...|.|||   ::..|||:||....|.....|| .:||:
Yeast   287 --------SYAVPT--FAQEGTYHSVPRSNALLFSDHQPVNLTVRLPRSTGT-PVPLS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_001261753.1	EEP	387..703	CDD:321002	89/368 (24%)
INP54	NP_014576.1	COG5411	1..371	CDD:227698	94/383 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810