Protein Alignment INPP5E and IP5PII

DIOPT Version :9

• Sequence 1: NP_001261753.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_567547.1
• Gene: IP5PII / 827526
• AraportID: AT4G18010
• Length: 646
• Species: Arabidopsis thaliana
• Alignment Length: 800
• Identity: 177/800 - (22%)
• Similarity: 283/800 - (35%)
• Gaps: 257/800 - (32%)

  Fly    35 KRPSKVEPHPVTPE----SPR--------LQQRPVS---ACGQYDVSFAKCNAD---------TS 75
            |||.:..|..|..:    .|:        :...|.|   .|...||....|..|         :.
plant     7 KRPERFWPSIVMNKWLNRKPKVYDFSEDEIDTEPESEDDVCSVKDVPNVHCVTDEDSHNGRRGSE 71

  Fly    76 ANHVNN---NGSTLKSQTLPLEKSHSGLISFHRRAKPSSSK-------------------GKNHS 118
            |:|.||   .|.:::          .|....|||.|..:.:                   ||..|
plant    72 ADHGNNISDGGVSVR----------GGYQRKHRRGKSETLRAQYINTKDIKVTVATWNVAGKRPS 126

  Fly   119 HRHSTDAGSQSDGGADVVM---RRKSPKHRSPNHNRFSHQFSLCCKAEKKPMTPPVTVRYNSIPD 180
            .....:....:|..:|:.:   :...|.:..   |.|.        ||.:          ..||.
plant   127 DDLEIEDWLSTDNPSDIYIIGFQEVVPLNAG---NVFG--------AEDR----------GPIPK 170

  Fly   181 SNSVLRRD-NLSLSWSMVDN----NSGSLHSSEGSSHRPRPSSECASAPESPVASK---TFFAHC 237
            ..|::||. |.|...|:.|.    |:.:||.|.             |||.||:.::   :..:|.
plant   171 WESIIRRTLNKSNKESVYDQSPSCNNNALHRSH-------------SAPSSPILAQEANSIISHV 222

  Fly   238 S----PAAASASVARSESLQNRSPIRPMAVSACRSRLRLKLYP---PGQELPPLQAATEP----- 290
            .    .|..|..:|.:|.:.        |.:|..|     |.|   |..:.|.|...:.|
plant   223 MVENLVADHSLDLATNEFID--------AATALPS-----LEPQRNPNMDWPELALDSNPQIVGS 274

  Fly   291 -GDIKRATTPQHMSSPNIATQPDGIEHIEEQPGVRFMSHENMTLQRQGSGSNLARQTLMAAHALN 354
             |.::|..:........:...|.|..        ||.| |...|:|..|           ...||
plant   275 EGKLRRVFSSNATLGFKLPENPSGAS--------RFAS-EARQLKRSRS-----------FETLN 319

  Fly   355 LIPADNARERSYLDGRLGSTSLLGPSELSRVLPQKEITVFVGTWNMNGHSPPKQLNDFVLPANVE 419
            |...|...|   :|.|..|:|  ...|.::::...         :.:|.|..:...|.....|..
plant   320 LSWNDIKEE---IDNRSSSSS--EAEEAAKIMHDD---------SSDGDSSSQDEEDGDKIRNSY 370

  Fly   420 HVPDIVVMGTQESTPDRFEWEVTIQETLGPSHVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASM 484
            .:|:.:|...::....:....:..::.:|             ::::|::||.|..:.:..:.:.:
plant   371 GLPEDLVEECRKVKDSQKYVRIVSKQMVG-------------IYVSVWIRRRLRRHVNNLKVSPV 422

  Fly   485 SVRTGSAFRTKGAVAISFCLFGTSMLFVTSHLTA-HQQKVKE-RVSDVKRIINA--------LDL 539
            .|........||:|:||..|:.:.|.||.||||: |:...:: |.:||..||..        .|.
plant   423 GVGLMGYMGNKGSVSISMTLYQSRMCFVCSHLTSGHKDGAEQRRNADVYEIIRRTRFASVLDTDQ 487

  Fly   540 PRNLPNQRHKNKDVTQNFDNVFWCGDLNFRL----GEPREKLLE--WIQNTKFPLPSHLPHGYMH 598
            ||.:|..           |.|||.||||:||    ||.|:.:.:  |.:             ..:
plant   488 PRTIPCH-----------DQVFWFGDLNYRLNMSDGEVRKLVSQKRWDE-------------LKN 528

  Fly   599 TDQLTSVLADGAAFRGFMEANITFPPTYKYDPGS-----QNFDTSSKQRAPAYTDRILYKYRQMQ 658
            :|||...|..|..|.|:.|..|.|||||||:..|     :|.....|:||||:.||||:..:.::
plant   529 SDQLIRELRRGHVFDGWREGPIKFPPTYKYEFDSDRYAGENLREPEKKRAPAWCDRILWLGKGIR 593

  Fly   659 GLVIRRQTLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVWALFRTLIRAGTDAIPLAAGLFSRD 723
            ....:|.                       .|..|||:||.::|.           :...:|..
plant   594 QECYKRS-----------------------EIRMSDHRPVTSIFN-----------VGVEVFDH- 623

  Fly   724 IYLEGMRRRLNNQYSGASAV 743
               ..::|.|:...:.||||
plant   624 ---RKLQRALHVNNAAASAV 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_001261753.1	EEP	387..703	CDD:321002	83/336 (25%)
IP5PII	NP_567547.1	PLN03191	1..646	CDD:215624	176/799 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1399831at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820