Protein Alignment INPP5E and Sh2d1a

DIOPT Version :9

• Sequence 1: NP_001261753.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_001102783.2
• Gene: Sh2d1a / 501502
• RGDID: 1562408
• Length: 126
• Species: Rattus norvegicus
• Alignment Length: 119
• Identity: 25/119 - (21%)
• Similarity: 46/119 - (38%)
• Gaps: 26/119 - (21%)

  Fly   564 GDLNFRLGEPREKLLEWIQNTKFPLPSHLPHGYM--HTDQLTSVLADGAAFRGFMEANITFPPTY 626
            |.::..:|   ||||         |.:.|...|:  .::.:..|......::|::         |
  Rat     9 GKISREMG---EKLL---------LATGLDGSYLLRDSESVPGVYCLCVLYQGYI---------Y 52

  Fly   627 KYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQGLVIRRQTLVPGVSTPTQPHVQ 680
            .|........:.|.:.||....|.   :|:::.|:...|....|:.||.|..|:
  Rat    53 TYRVSQTETGSWSAETAPGVHKRF---FRKVKNLISAFQKPDQGIVTPLQYPVE 103

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_001261753.1	EEP	387..703	CDD:321002	25/119 (21%)
Sh2d1a	NP_001102783.2	SH2_SAP1a	2..104	CDD:198263	25/119 (21%)
		Interaction with FYN SH3 domain. /evidence=ECO:0000250|UniProtKB:O88890	67..92		6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..126		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900