Sequence 1: | NP_001261753.1 | Gene: | INPP5E / 39404 | FlyBaseID: | FBgn0036273 | Length: | 747 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001017915.1 | Gene: | INPP5D / 3635 | HGNCID: | 6079 | Length: | 1189 | Species: | Homo sapiens |
Alignment Length: | 752 | Identity: | 176/752 - (23%) |
---|---|---|---|
Similarity: | 277/752 - (36%) | Gaps: | 231/752 - (30%) |
- Green bases have known domain annotations that are detailed below.
Fly 4 SSAGSEERITSSTSSPRSGHKTASSLFGLLSKRPSKVEPHPVTPESPRLQQRPVSACGQYDVSFA 68
Fly 69 KCNADTSANHVNNNGSTLKSQTLPLEKSHSGLISFHRRAKPSSSKGKNHSHRHSTDAGSQSDGGA 133
Fly 134 DVVMRRKSPKHRSPNHNRFSHQFSLCCKAEKKPMTP----PVTVRYNSIPDSNSVLRRDNL-SLS 193
Fly 194 WSMVDNNSGSLHSSEGSSHRPRPSSECASAPESPVASKTFFAHCSPAAASASVARSESLQNRSPI 258
Fly 259 RPMAVSACRSRLRLKLYPPGQELPPLQAATEPGDIKRATTPQHMSSPNIATQPDGIEHIEEQPGV 323
Fly 324 RFMSHENMTLQRQGSGSNLARQTLMAAHALN----LIPADN----ARERSYLDG--RLGSTSLLG 378
Fly 379 PSELSRVLPQKE---ITVFVGTWNMNGHSPPKQLNDFVLPA--------NVEHVP-DIVVMGTQE 431
Fly 432 STPDRFEWEVTIQETLGP-SHVLFHATTLGTLHLAVYMRRDLIWYCSV-----PEDASM------ 484
Fly 485 -SVRTGSA--FRTKGAVAISFCLFGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLPRNLPNQ 546
Fly 547 RHKNKDVTQNFDNVFWCGDLNFRLGEP---REKLLEWIQNTKF-PLPSHLPHGYMHTDQLTSVLA 607
Fly 608 DGAAFRGFMEANITFPPTYKYDPGSQNFDTSSKQRA-------PAYTDRILYKYRQMQGLVIRRQ 665
Fly 666 TLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVWALF 702 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
INPP5E | NP_001261753.1 | EEP | 387..703 | CDD:321002 | 107/354 (30%) |
INPP5D | NP_001017915.1 | SH2_SHIP | 1..102 | CDD:198206 | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 103..132 | ||||
SH3-binding 1 | 124..129 | ||||
INPP5c_SHIP1-INPP5D | 404..710 | CDD:197334 | 105/347 (30%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 870..906 | ||||
PHA03307 | 899..>1127 | CDD:223039 | |||
NPXY motif 1 | 912..915 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 922..1189 | ||||
SH3-binding 2 | 969..974 | ||||
Interaction with DAB2. /evidence=ECO:0000250 | 1016..1030 | ||||
NPXY motif 2 | 1019..1022 | ||||
SH3-binding 3 | 1040..1051 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5411 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |