Protein Alignment INPP5E and Ocrl

DIOPT Version :10

• Sequence 1: NP_648566.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_558090.4
• Gene: Ocrl / 3291116
• VectorBaseID: AGAMI1_001352
• Length: 876
• Species: Anopheles gambiae
• Alignment Length: 595
• Identity: 145/595 - (24%)
• Similarity: 227/595 - (38%)
• Gaps: 164/595 - (27%)

  Fly   171 VTVRYNSIPDSNSVLRRDNLSLSWSMVDNN-------------SGSLHSSEGSSHRPRPSSECAS 222
            ||.::.   :..|||.   :..::.:|.||             |.:|.|...|...|...|:...
Mosquito    14 VTQKFR---EGESVLA---ILAAYQIVGNNFQNRLLVTVSSSESAALFSFSVSREPPESISDLTI 72

  Fly   223 APESPVASKTFFAHCSPAAASASVARSESLQNRSPI-----RPMAVSACRSRL--RLKLYPPGQE 280
            ....|: :::||.:...:..|.|..:.....:..|.     ....:||.:...  .||.......
Mosquito    73 VAVVPI-NESFFVNTESSFGSVSSHQFTVFSDNQPTTYYYHATEEISAAKEHFLTSLKNLKASYR 136

  Fly   281 LPPLQAATEPGDIKRATTPQHMSSPNIATQPDGIEHIEEQPGVRFMSHENMTLQRQGSGSNLARQ 345
            ..|:.:   ||    |....|...|           .:|:.|:       :.:.|..:..:.|.:
Mosquito   137 AVPVHS---PG----AFDWLHYYKP-----------ADERTGL-------LAIDRSVADGSQAPK 176

  Fly   346 TLMAAHALNLIPADNARERSYLDGRLGSTSLLGPSELSRVLPQKEITVFVGTWNMNGH-SPPKQL 409
            |            .:|:.|..|:.|....::..|..           |:..|||:||. |...:|
Mosquito   177 T------------RDAKFREELERRRHEYTVYEPYH-----------VYTATWNVNGQTSETIEL 218

  Fly   410 NDFVLPANVEHVPDIVVMGTQESTPDRFEWEVTIQETLGPSHVLFHAT---------TLGTLH-- 463
            .:::  |..:..|||..:|.||     .||.        |..:|.:.|         .:..||
Mosquito   219 PEWL--ATTDSPPDIYAVGFQE-----IEWT--------PEKILMNETKIDRTWVDKVMSGLHKG 268

  Fly   464 ---------------LAVYMRRDLIWYCSVPEDASMSVRTGS-AFRTKGAVAISFCLFGTSMLFV 512
                           |.|.::..:  |..:.:..:.:|.||: .:..||.|.:||.|......||
Mosquito   269 AIYTELASVRLVGMMLTVAVKSTI--YPKINDCLTAAVGTGTLKWGNKGGVGVSFKLNEALFCFV 331

  Fly   513 TSHLTAHQQKVKERVSDVKRIINALDLP-----RNLPNQRHKNKDVTQNFDNVFWCGDLNFRLGE 572
            .:||.||.|:|:.|..|...||..:...     |::....|           :||.||||:||..
Mosquito   332 NTHLAAHTQEVERRNDDHDDIIRRMSFDNGFRMRSIDEHHH-----------IFWIGDLNYRLDG 385

  Fly   573 PREKLLEWIQNTKFPLPSHLPHGYMHTDQLTSVLADGAAFRGFMEANITFPPTYKYDPGSQNFDT 637
            | |...|:: |.|....:.|   |.| |||.........||.:.|..|.|||||||:||:..:|:
Mosquito   386 P-EVSQEYV-NRKDRDYNQL---YQH-DQLYVEKRRNRIFRDYKEGKILFPPTYKYNPGTDEWDS 444

  Fly   638 SSKQRAPAYTDRILYKYRQMQGLVIRRQTLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVWALF 702
            |.|.|.||:.||||:|.::                      ::.|.|:||..:..||||||:|.|
Mosquito   445 SEKSRTPAWCDRILWKGQR----------------------IEMLRYNSVMQLRKSDHKPVYADF 487

  Fly   703 RTLIRAGTDA 712
            :...:|...|
Mosquito   488 KVDAQAKDQA 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_648566.1	EEP	387..703	CDD:469791	102/348 (29%)
Ocrl	XP_558090.4	None