Protein Alignment INPP5E and Inpp5k

DIOPT Version :10

• Sequence 1: NP_648566.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_001013881.1
• Gene: Inpp5k / 287533
• RGDID: 1359130
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 363
• Identity: 97/363 - (26%)
• Similarity: 145/363 - (39%)
• Gaps: 83/363 - (22%)

  Fly   373 STSLLGPSELSRVLPQKEITVFVGTWNMNGHSPPKQLNDFVLPANVEHVPDIVVMGTQES----- 432
            :.||..||....::    :::.|.|||:...:|...|:|.:...|.:...||.::|.||.
  Rat     3 TASLRKPSAPKELM----LSIHVVTWNVASAAPTVDLSDLLQLNNEDLNLDIYIIGLQEMNYGII 63

  Fly   433 ---TPDRFE--WEVTIQETLGPSH-VLFHATTLGTLHLAVYMRRDLIWYCSVPEDASMSVRTGSA 491
               :...||  |.....:.|.|.: |......:..|.|.|:.:...:.|..:....|:.......
  Rat    64 SLLSDAAFEDPWSSFFMDMLSPLNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGY 128

  Fly   492 FRTKGAVAISFCLFGTSMLFVTSHLTAHQQKVKERVSDVKRIINAL-----DLPRNLPNQRHKNK 551
            :..||.:.|...|:|..:..|..||..|.....:|:....||:.:|     |:|..|
  Rat   129 WGNKGGINICLKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNIL-------- 185

  Fly   552 DVTQNFDNVFWCGDLNFRLGE------------PREKLLEWIQNTKFPLPSHLPHGYMHTDQLTS 604
                :.|.:.|.||:|||:.:            .|.|.| |                 ..|||..
  Rat   186 ----DHDLILWFGDMNFRIEDFGLLFVQECITKKRYKEL-W-----------------EKDQLFI 228

  Fly   605 VLADGAAFRGFMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQGLVIRRQTLVP 669
            ........|.|.|..:.||||||:|..|.|:|||.|:|.||:|||||::        ::||   |
  Rat   229 AKKQDQLLREFQEGPLLFPPTYKFDRHSNNYDTSEKKRKPAWTDRILWR--------LKRQ---P 282

  Fly   670 GVSTP-----TQPHVQCLLYDSVPSITTSDHKPVWALF 702
            ..:.|     ||..     |.|..:.:.||||||...|
  Rat   283 AKANPSGFLLTQKD-----YVSHMTYSISDHKPVTGTF 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_648566.1	EEP	387..703	CDD:469791	93/349 (27%)
Inpp5k	NP_001013881.1	EEP	17..317	CDD:469791	93/345 (27%)
		SKICH	328..428	CDD:465482