Protein Alignment INPP5E and inpp-1

DIOPT Version :9

• Sequence 1: NP_001261753.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_001255511.1
• Gene: inpp-1 / 177970
• WormBaseID: WBGene00012016
• Length: 432
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 88/328 - (26%)
• Similarity: 144/328 - (43%)
• Gaps: 35/328 - (10%)

  Fly   381 ELSRVLPQKEITVFVGTWNMN--GHSPPKQLNDFVLPANVEHVPDIVVMGTQE--STPDRFEWE- 440
            ::...:..:::.|...|||:|  |......|...:.....|...||..:..||  ||...|..|
 Worm    97 DVIEAMGDRKLKVCTVTWNINEKGVKILSHLAQKIAERGQEMDSDIFFISLQEIPSTAPTFHEEA 161

  Fly   441 VTIQETLGPSHVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASM-SVRTGSAFRTKGAVAISFCL 504
            :.|.|.:...|.|:.:....:..:.|::|:..:.|...|:.:.: |.......|||||:|:...|
 Worm   162 LRILEPVLNGHRLYLSHRAWSQMVIVFIRQKHLRYAIQPQVSFIASGAMAKPVRTKGAIAVCLRL 226

  Fly   505 FGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLPRNLPNQRHKNKDVTQNFDNVFWCGDLNFR 569
            :...::.:..||:  ....::|:.|..:::..|..|:......|. ||.....|.|.|.||||||
 Worm   227 YQRFIVLIGCHLS--HATPQQRIQDYAKVVRTLRFPQLARFHAHA-KDEIFGSDVVLWIGDLNFR 288

  Fly   570 LGEPREKLLEWIQNTKFPLPSHLPHGYMHTDQLTSVLADGAAFRGFMEANITFPPTYKYDPGSQN 634
            :  ..|..::|....|  :..........|::|.|......||..|.||.|.||||:|::|.:.|
 Worm   289 V--TVESNVDWRDPEK--ITEKTFRDVFETEELASHRKKQLAFTDFKEAPIKFPPTHKFEPDTDN 349

  Fly   635 FDTSSKQRAPAYTDRILYKYRQMQGLVIRRQTLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVW 699
            :   ..:|.|::|||:|:..|..:.|                   |.:.||.:...|.||||.|:
 Worm   350 Y---VPKRIPSFTDRVLFWVRNSEWL-------------------QNIQYDCMRGTTPSDHKAVF 392

  Fly   700 ALF 702
            |.|
 Worm   393 ATF 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_001261753.1	EEP	387..703	CDD:321002	88/322 (27%)
inpp-1	NP_001255511.1	IPPc	105..399	CDD:214525	88/320 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000945
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104600
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740