Protein Alignment INPP5E and Synj

DIOPT Version :10

• Sequence 1: NP_648566.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_061517465.1
• Gene: Synj / 1280512
• VectorBaseID: AGAMI1_004276
• Length: 1255
• Species: Anopheles gambiae
• Alignment Length: 515
• Identity: 142/515 - (27%)
• Similarity: 208/515 - (40%)
• Gaps: 139/515 - (26%)

  Fly   336 QGSGSNLARQTLMAAHAL--NLIPADNARER------------SYLDGR----LGSTSLLGPSEL 382
            || ||.|......||..:  ||:  ||:::.            |.|..|    |.|..|..|:.:
Mosquito   468 QG-GSKLMDGARSAARTIQNNLL--DNSKQEAIDVLLVGSTLSSELADRARILLPSNMLHAPTPV 529

  Fly   383 SRVLPQK--------EITVFVGTWNMNG---------------------H--SPPKQLNDFVLPA 416
            .|.:.::        ...|..||:|:||                     |  :..:.|.||....
Mosquito   530 LREMCKRYEEYVNPLVFRVACGTYNVNGGKHFRSVAYKDVSLADWLLDCHRLARSRSLVDFSQVD 594

  Fly   417 NVEHVP-DIVVMGTQE------------STPDRFEWEVTIQETLG--PSHVLFHATTLGTLHLAV 466
            :....| ||..:|.||            |:.:...|...:|:.:.  ..:||.....|..:.|.:
Mosquito   595 DSNEPPVDIFAIGFQEIVDLNASNIVAASSDNAKAWAEELQKVVSRDREYVLLTYQQLVGVCLYI 659

  Fly   467 YMR-------RDLIWYCSVPEDASMSVRT--GSAFRTKGAVAISFCLFGTSMLFVTSHLTAHQQK 522
            |:|       ||:...|         |:|  |.|...|||.||.|.|.|||:.||.:|..|.|.:
Mosquito   660 YIRPQHAQYIRDVAIDC---------VKTGLGGATGNKGAAAIRFVLHGTSICFVCAHFAAGQSQ 715

  Fly   523 VKERVSDVKRIINALDLPRNLPNQRHKNKDVTQNFDNVFWCGDLNFRLGEPREKLLEWIQNTKFP 587
            |.||.:|...|...:..|.....:.|         |.:|||||.|:|:...:::|.|.::.:...
Mosquito   716 VAERNADYAEITRKIAFPMGRSLKSH---------DYIFWCGDFNYRIDMDKDELREALKQSPHD 771

  Fly   588 LPSHLPHGYMHTDQLTSVLADGAAFRGFMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILY 652
            |.:.|.:     |||......|:.|..|:|..|:||||||||..|.::|||.|.||||:|||:|:
Mosquito   772 LTAVLQY-----DQLRIQQNAGSVFNEFLEGEISFPPTYKYDLFSDDYDTSEKCRAPAWTDRVLW 831

  Fly   653 KYRQMQGLVIRRQTLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVWAL---------------- 701
            :.|:......|.....||          .|::.....:..|||:||.|:
Mosquito   832 RRRKQSPDADRHPGWNPG----------RLVHYGRAELKQSDHRPVIAMIDIEVHYIDPERRSTV 886

  Fly   702 FRTLIR-----AGTDAI----PLAAGLFSRD-----IYLEGMRRRLNNQYSGASAVCVLQ 747
            |..:||     .||..|    |.|||..|.|     ||.|.:...|..:.:....|.:::
Mosquito   887 FGDVIRDLGPPDGTILIQACSPSAAGTDSGDEDEGSIYDENLMAALIQELTQIGEVTLVR 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_648566.1	EEP	387..703	CDD:469791	106/386 (27%)
Synj	XP_061517465.1	None