Protein Alignment INPP5E and Synj1

DIOPT Version :9

• Sequence 1: NP_001261753.1
• Gene: INPP5E / 39404
• FlyBaseID: FBgn0036273
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_011244377.1
• Gene: Synj1 / 104015
• MGIID: 1354961
• Length: 1714
• Species: Mus musculus
• Alignment Length: 451
• Identity: 138/451 - (30%)
• Similarity: 189/451 - (41%)
• Gaps: 128/451 - (28%)

  Fly   332 TLQRQ--GSGSNLARQTLMAAHALNLIPADNARERSYLDGRLGSTSLLGPSE------LSRVLPQ 388
            |:|..  .|....|...|:..:.||...||.||       .|.:|..|..||      .|:||..
Mouse   609 TIQNNFFDSSKQEAIDVLLLGNTLNSDLADKAR-------ALLTTGSLRVSEQTLQSASSKVLKN 666

  Fly   389 -----------KEITVFVGTWNMNGHSPPKQ----------LNDFVLP----ANVEHV------- 421
                       |:|.|.|||||:||   .||          |.|::|.    |.::..
Mouse   667 MCENFYKYSKPKKIRVCVGTWNVNG---GKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKP 728

  Fly   422 PDIVVMGTQE------------STPDRFEWEVTIQETLG--PSHVLFHATTLGTLHLAVYMR--- 469
            .||..:|.:|            ||.::..|.|.:|:|:.  ..:||..:..|..:.|.|::|
Mouse   729 TDIFAIGFEEMVELNAGNIVNASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQH 793

  Fly   470 ----RDLIWYCSVPEDASMSVRT--GSAFRTKGAVAISFCLFGTSMLFVTSHLTAHQQKVKERVS 528
                ||:         |..:|:|  |.|...||||||......||:.||.||..|.|.:||||..
Mouse   794 APFIRDV---------AVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNE 849

  Fly   529 DVKRIINALDLPRNLPNQRHKNKDVTQNFDNVFWCGDLNFRLGEPREKLLEWIQNTKFPLPSHLP 593
            |...|...|..|.......|         |.||||||.|:|:..|.|::.|.|:...:
Mouse   850 DFVEIARKLSFPMGRMLFSH---------DYVFWCGDFNYRIDLPNEEVKELIRQQNW------- 898

  Fly   594 HGYMHTDQLTSVLADGAAFRGFMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYR--- 655
            ...:..|||.:....|..||||:|..:||.||||||..|:::|||.|.|.||:|||:|::.|
Mouse   899 DSLIAGDQLINQKNAGQIFRGFLEGKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWP 963

  Fly   656 ---------------QMQGLVIRRQTLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVWAL 701
                           |.:..::  .|..||.          ||:.....:.||||:||.||
Mouse   964 FDRSAEDLDLLNASFQDESKIL--YTWTPGT----------LLHYGRAELKTSDHRPVVAL 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INPP5E	NP_001261753.1	EEP	387..703	CDD:321002	119/388 (31%)
Synj1	XP_011244377.1	COG5329	204..627	CDD:227637	4/17 (24%)
		INPP5c_Synj1	680..1015	CDD:197332	118/373 (32%)
		RRM_SF	1014..1155	CDD:388407
		PHA03247	<1207..1609	CDD:223021

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810