DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sms and SRM

DIOPT Version :9

Sequence 1:NP_001287045.1 Gene:Sms / 39403 FlyBaseID:FBgn0036272 Length:458 Species:Drosophila melanogaster
Sequence 2:XP_016857668.1 Gene:SRM / 6723 HGNCID:11296 Length:316 Species:Homo sapiens


Alignment Length:211 Identity:59/211 - (27%)
Similarity:99/211 - (46%) Gaps:37/211 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 IEYDIDKVVFEARSPFQKIQIMHSKTLGNMLLLDELQNIAESD-LIYTETL----MCRGVENYEG 196
            :...:::::...||.:|.|.:..|||.||:|:||.:....|.| ..|.|.:    :|   .:...
Human    33 LSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLC---SHPNP 94

  Fly   197 KEICILGGGDGALLYELLKE-NPKHVVMLEIDELVMQTCNKYL-NVICGDVLEKRKGDQYEIIVG 259
            :::.|:|||||.:|.|::|. :.:.||..||||.|:|...|:| .:..|     ....:..:.||
Human    95 RKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIG-----YSSSKLTLHVG 154

  Fly   260 DCVEYLKKFIAEGRKFDYVFGDLTDIPITDAPEGETWDFIRTIFEHSF-----KVLKPDGKYLTH 319
            |..|::|:   ....||.:..|.:|      |.|..    .::|:.|:     ..||.||.....
Human   155 DGFEFMKQ---NQDAFDVIITDSSD------PMGPA----ESLFKESYYQLMKTALKEDGVLCCQ 206

  Fly   320 GNGSTCK-VQLRLFEE 334
            |.   |: :.|.|.:|
Human   207 GE---CQWLHLDLIKE 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SmsNP_001287045.1 AdoMet_MTases 137..362 CDD:302624 59/211 (28%)
SRMXP_016857668.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0421
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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