DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sms and spds-1

DIOPT Version :9

Sequence 1:	NP_001287045.1	Gene:	Sms / 39403	FlyBaseID:	FBgn0036272	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001367196.1	Gene:	spds-1 / 174914	WormBaseID:	WBGene00012909	Length:	366	Species:	Caenorhabditis elegans

Alignment Length:	234	Identity:	66/234 - (28%)
Similarity:	108/234 - (46%)	Gaps:	34/234 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 IDKVVFEARSPFQKIQIMHSKTLGNMLLLDELQNIAESD-LIYTETLMCRGV-ENYEGKEICILG 203
            :.||:|..:|.:|.:.:..|.|.||:|:||.:....|.| ..|.|.|....: .:.:.|.:.|:|
Worm    52 VKKVLFHEKSKYQDVLVFESTTYGNVLVLDGIVQATERDEFSYQEMLAHLPMFAHPDPKRVLIIG 116

  Fly   204 GGDGALLYELLK-ENPKHVVMLEIDELVMQTCNKYL-NVICGDVLEKRKGDQYEIIVGDCVEYLK 266
            ||||.:|.|:|| |:.:.|.|.||||:|:....|:| .:.||....|     .::..||..|:||
Worm   117 GGDGGILREVLKHESVEKVTMCEIDEMVIDVAKKFLPGMSCGFSHPK-----LDLFCGDGFEFLK 176

  Fly   267 KFIAEGRKFDYVFGDLTDIPITDAPEGETWDFIRTIFEHSF-----KVLKPDGKYLTHGNGSTCK 326
            .   ...:||.:..|.:| |:..|         .::|..|:     ..||.||  :....|....
Worm   177 N---HKNEFDVIITDSSD-PVGPA---------ESLFGQSYYELLRDALKEDG--ILSSQGECPW 226

  Fly   327 VQLRLFEEQLNLLR---PKVKFTTTKAFVPSFMEEWLFY 362
            :.::|....::..|   |..|:..  ..||::....:.|
Worm   227 LDMKLISTVIHSARDLFPVAKYAV--GSVPTYTSGLMGY 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sms	NP_001287045.1	AdoMet_MTases	137..362	CDD:302624	65/232 (28%)
spds-1	NP_001367196.1	AdoMet_MTases	7..366	CDD:418430	66/234 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910