DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pbgs and Alad

DIOPT Version :9

Sequence 1:	NP_001261752.1	Gene:	Pbgs / 39402	FlyBaseID:	FBgn0036271	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_037031.1	Gene:	Alad / 25374	RGDID:	2083	Length:	330	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	195/320 - (60%)
Similarity:	243/320 - (75%)	Gaps:	6/320 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LHSGMHHATLRQLQESGCEIAPHNLMYPVFIVSNDDDVQPIASMPGISRFGLNRLKEHLEPLVAK 69
            ||||..|..||..|.:...::..||:||:|:....||||||||:||::|:|:|:|:|.|.|||..
  Rat     7 LHSGYFHPLLRAWQTTPSTVSATNLIYPIFVTDVPDDVQPIASLPGVARYGVNQLEEMLRPLVEA 71

  Fly    70 GLSSVLLFGVVDPDMKDEQASNADSAKNPVVLALPKLREWFPDLLIACDVCICPYSSHGHCGLLG 134
            ||..||:|||.....||||.|.|||..:|.:.|:..||:.||.||:|||||:|||:||||||||.
  Rat    72 GLRCVLIFGVPSRVPKDEQGSAADSEDSPTIEAVRLLRKTFPTLLVACDVCLCPYTSHGHCGLLS 136

  Fly   135 ETG---LENGPSIKRIAEIAVAYAKAGAHIVAPSDMMDNRVKAIKQALIDAQM-NSVSLLAYSAK 195
            |.|   .|.  |.:|:||:|:||||||..:||||||||.||:|||.||:...: |.||:::||||
  Rat   137 ENGAFLAEE--SRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKAALLKHGLGNRVSVMSYSAK 199

  Fly   196 FTSNFYGPFREAAQSAPKFGDRRCYQLPSGSRSLAMRAIQRDVAEGADMLMVKPGMPYLDILRST 260
            |.|.||||||:||||:|.||||||||||.|:|.||:||:.||:.||||:||||||:||||:::..
  Rat   200 FASCFYGPFRDAAQSSPAFGDRRCYQLPPGARGLALRAVARDIQEGADILMVKPGLPYLDMVQEV 264

  Fly   261 KDSYPYHTLYVYQVSGEFAMLYHAAKAGAFDLKDAVLEAMKGFRRAGADCIITYYTPFLL 320
            ||.:|...|.|||||||||||:|.||||||||:.||||:|..|||||||.||||:.|.||
  Rat   265 KDKHPELPLAVYQVSGEFAMLWHGAKAGAFDLRTAVLESMTAFRRAGADIIITYFAPQLL 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pbgs	NP_001261752.1	eu_ALAD_PBGS_cysteine_rich	6..323	CDD:240128	194/319 (61%)
Alad	NP_037031.1	eu_ALAD_PBGS_cysteine_rich	8..327	CDD:240128	194/319 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339333
Domainoid	1	1.000	378	1.000	Domainoid score	I823
eggNOG	1	0.900	-	-		E1_COG0113
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1943
OMA	1	1.010	-	-		QHG61014
OrthoDB	1	1.010	-	-		D507462at33208
OrthoFinder	1	1.000	-	-		FOG0004339
OrthoInspector	1	1.000	-	-		oto95585
orthoMCL	1	0.900	-	-		OOG6_101254
Panther	1	1.100	-	-	LDO	PTHR11458
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3061
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770