Protein Alignment Pbgs and ALAD

DIOPT Version :9

• Sequence 1: NP_001261752.1
• Gene: Pbgs / 39402
• FlyBaseID: FBgn0036271
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_001003945.1
• Gene: ALAD / 210
• HGNCID: 395
• Length: 359
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 184/283 - (65%)
• Similarity: 225/283 - (79%)
• Gaps: 2/283 - (0%)

  Fly    40 DDVQPIASMPGISRFGLNRLKEHLEPLVAKGLSSVLLFGVVDPDMKDEQASNADSAKNPVVLALP 104
            ||:|||.|:||::|:|:.||:|.|.|||.:||..||:|||.....|||:.|.|||.::|.:.|:.
Human    71 DDIQPITSLPGVARYGVKRLEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSAADSEESPAIEAIH 135

  Fly   105 KLREWFPDLLIACDVCICPYSSHGHCGLLGETG-LENGPSIKRIAEIAVAYAKAGAHIVAPSDMM 168
            .||:.||:||:|||||:|||:||||||||.|.| .....|.:|:||:|:||||||..:|||||||
Human   136 LLRKTFPNLLVACDVCLCPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMM 200

  Fly   169 DNRVKAIKQALIDAQM-NSVSLLAYSAKFTSNFYGPFREAAQSAPKFGDRRCYQLPSGSRSLAMR 232
            |.||:|||:||:...: |.||:::|||||.|.||||||:||:|:|.||||||||||.|:|.||:|
Human   201 DGRVEAIKEALMAHGLGNRVSVMSYSAKFASCFYGPFRDAAKSSPAFGDRRCYQLPPGARGLALR 265

  Fly   233 AIQRDVAEGADMLMVKPGMPYLDILRSTKDSYPYHTLYVYQVSGEFAMLYHAAKAGAFDLKDAVL 297
            |:.|||.|||||||||||||||||:|..||.:|...|.||.||||||||:|.|:|||||||.|||
Human   266 AVDRDVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVL 330

  Fly   298 EAMKGFRRAGADCIITYYTPFLL 320
            |||..|||||||.|||||||.||
Human   331 EAMTAFRRAGADIIITYYTPQLL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pbgs	NP_001261752.1	eu_ALAD_PBGS_cysteine_rich	6..323	CDD:240128	184/283 (65%)
ALAD	NP_001003945.1	eu_ALAD_PBGS_cysteine_rich	68..356	CDD:240128	184/283 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145639
Domainoid	1	1.000	383	1.000	Domainoid score	I834
eggNOG	1	0.900	-	-		E1_COG0113
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16
Inparanoid	1	1.050	392	1.000	Inparanoid score	I1994
Isobase	1	0.950	-	0	Normalized mean entropy	S746
OMA	1	1.010	-	-		QHG61014
OrthoDB	1	1.010	-	-		D507462at33208
OrthoFinder	1	1.000	-	-		FOG0004339
OrthoInspector	1	1.000	-	-		oto88445
orthoMCL	1	0.900	-	-		OOG6_101254
Panther	1	1.100	-	-	LDO	PTHR11458
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R555
SonicParanoid	1	1.000	-	-		X3061
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750