Protein Alignment app and PFA3

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_014073.1
• Gene: PFA3 / 855390
• SGDID: S000005270
• Length: 336
• Species: Saccharomyces cerevisiae
• Alignment Length: 262
• Identity: 74/262 - (28%)
• Similarity: 103/262 - (39%)
• Gaps: 65/262 - (24%)

  Fly    49 TCILI-TGTSALFFAFDCP--FLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEA 110
            ||:.| |....|......|  |||.:|   :|.:...||.:     .:.....|| .|....|..
Yeast    17 TCLYIWTAYITLTRIHQIPRWFLALTI---VPTLAVALYTY-----YKVIARGPG-SPLDFPDLL 72

  Fly   111 AYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDH 175
            .:..|..|  |.|..|   |...:|..|......:.:.|..|.:::|.|..|||.||.|:.:.||
Yeast    73 VHDLKAAE--NGLELP---PEYMSKRCLTLKHDGRFRVCQVCHVWKPDRCHHCSSCDVCILKMDH 132

  Fly   176 HCPWVGNCVGKRNYRFFYLFLV---SLAFLAVFIFSCSVTHLVLLMKKEHEV--------FN--- 226
            ||||...|.|.||.:||..||:   ..||| |.|::|            :|:        ||
Yeast   133 HCPWFAECTGFRNQKFFIQFLMYTTLYAFL-VLIYTC------------YELGTWFNSGSFNREL 184

  Fly   227 ---------VIKAAPFTVIVVFICFFSIWSV------IGLAGFHTY-----LTTSDQTTNEDLKG 271
                     ::..|.|..::.|.| |||:.|      |.:.|...|     :......|||.|:.
Yeast   185 IDFHLLGVALLAVAVFISVLAFTC-FSIYQVCKNQTTIEVHGMRRYRRDLEILNDSYGTNEHLEN 248

  Fly   272 SF 273
            .|
Yeast   249 IF 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	47/157 (30%)
PFA3	NP_014073.1	COG5273	1..304	CDD:227598	74/262 (28%)