Protein Alignment app and PFA5

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_010747.1
• Gene: PFA5 / 852070
• SGDID: S000002867
• Length: 374
• Species: Saccharomyces cerevisiae
• Alignment Length: 223
• Identity: 44/223 - (19%)
• Similarity: 86/223 - (38%)
• Gaps: 38/223 - (17%)

  Fly    75 AIPIVGAVLYFFTMSSLLRTTFTDPG---------VIPRASNDEAAYIEKQIEVPNSLNSP--TY 128
            |:..:..|:.|..:..::   ...||         ::|.||.::.:...:...|......|  .|
Yeast    59 AVCFLDVVVIFIWLQIVI---LVGPGTQPHVAPFLILPIASEEKTSNTSQNTSVEYDAVVPPKCY 120

  Fly   129 RPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFY 193
            :..|....:          :|..|:..:..|..|.|...:|:.||||:|.|:|..:|:.|||.|.
Yeast   121 QSDPHGYPI----------WCSECQSLKMERTHHSSELGHCIPRFDHYCMWIGTVIGRDNYRLFV 175

  Fly   194 LFLVSLAFLAVFIFSCSVTHLVLLMKKEHEV-----FNVIKAAPFTVIVVFICFFSIWSV-IGLA 252
            .|....:.|.:.::.....::.::.:..|..     .|:|....|.::.        |.: ..|.
Yeast   176 QFAAYFSTLLLIMWVSICVYIRIITQHNHNYSPNLNANIISTLVFAILG--------WLLTASLL 232

  Fly   253 GFHTYLTTSDQTTNEDLKGSFSSKGGPR 280
            ....:..:.::|:.|.:..|...|.|.|
Yeast   233 ASSIFYMSQNKTSLEAIIDSKRKKFGTR 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	28/129 (22%)
PFA5	NP_010747.1	COG5273	9..335	CDD:227598	44/223 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810