Protein Alignment app and ZDHHC16

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_006718084.1
• Gene: ZDHHC16 / 84287
• HGNCID: 20714
• Length: 384
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 80/353 - (22%)
• Similarity: 132/353 - (37%)
• Gaps: 131/353 - (37%)

  Fly    45 VFYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVL--------YFFTMSSLLRTTF----- 96
            ||.:..|::|| |.:..|:.|         .:|::....        :|::..:|:...|
Human    82 VFVVLVIVLTG-SIVAIAYLC---------VLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQA 136

  Fly    97 --TDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPR 159
              |.||..|:..||.|                                ||.:  |..|...:|.|
Human   137 ITTPPGYPPQGRNDIA--------------------------------TVSI--CKKCIYPKPAR 167

  Fly   160 ASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCS-------------V 211
            ..|||:|:.||.:.||||||:.||||..|:|:|:.|...:....|:   ||             :
Human   168 THHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVY---CSYGSWDLFREAYAAI 229

  Fly   212 THLVLLMKKE-----HEVFNVIKAAPFT----------VIVVFICFF--SIWSVIGLA-----GF 254
            ..:..|.|.:     ::.::......|:          |.:.|:|..  |..|.:.||     .:
Human   230 EKMKQLDKNKLQAVANQTYHQTPPPTFSFRERMTHKSLVYLWFLCSLRPSFLSSVALALGALTVW 294

  Fly   255 HTYLTTSDQTT-----NEDLKGSFSSKGGPRT-QNPYSRGNICLNCCHILCGPMTPSLIDRRGIA 313
            |..|.:..:|:     |:..:....:||  |. :|||:.|  ||:...:..|      :|
Human   295 HAVLISRGETSIERHINKKERRRLQAKG--RVFRNPYNYG--CLDNWKVFLG------VD----- 344

  Fly   314 TDEFIQQMQHQSSPRHALSDV-LSASHM 340
                        :.||.|:.| |.:||:
Human   345 ------------TGRHWLTRVLLPSSHL 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	41/163 (25%)
ZDHHC16	XP_006718084.1	zf-DHHC	155..312	CDD:279823	40/161 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810