DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment app and AT5G50020

DIOPT Version :9

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_001190503.1	Gene:	AT5G50020 / 835066	AraportID:	AT5G50020	Length:	444	Species:	Arabidopsis thaliana

Alignment Length:	421	Identity:	133/421 - (31%)
Similarity:	198/421 - (47%)	Gaps:	87/421 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINP-----AIPIV 79
            |.:|.:.|.|||...|.|:..|.......|.:||......|..|....|...:.|     ...:.
plant    34 RVFEAWKGSNKFLFGGRLIFGPDAWSIPFTFLLIITPVCFFSVFVATHLRRELLPNNAGHVFLVA 98

  Fly    80 GAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPP----PRTKEVLVK 140
            |.:...|.:..|..|:..|||::||.|:..    |:::....:::|...:.|    ||||||:|.
plant    99 GVLFTVFVLILLFLTSARDPGIVPRNSHPP----EEELCYDTTVSSDGRQTPTVQIPRTKEVMVY 159

  Fly   141 GQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVF 205
            |.:|::|||.||.::||||.||||:|:|||:||||||||||.|:|.||||:|::|:.|...|.::
plant   160 GVSVRVKYCDTCMLYRPPRCSHCSICNNCVERFDHHCPWVGQCIGVRNYRYFFMFVSSATILCIY 224

  Fly   206 IFSCSVTHLVLLMKKEHE--VFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNED 268
            |||.|..::.:|| ..|:  |:..::.:|:.|:::..||.|:|.|.||.|||.||.:::|||.|
plant   225 IFSMSALYIKVLM-DNHQGTVWRAMRESPWAVMLMIYCFISLWFVGGLTGFHLYLISTNQTTYE- 287

  Fly   269 LKGSFSSKGGPRTQNPYSRGNICL-NCCHILCGPMTPSLIDRRG-----------IAT------- 314
               :|..:...|. |.|:||  |. |.....|..:.||..|.|.           :||
plant   288 ---NFRYRSDNRI-NVYNRG--CSNNFFETFCSKVKPSRNDFRAFIKEEPPRNITLATTWERPEE 346

  Fly   315 -------------------DEFIQQMQHQSSPRHALSDVLSASHMVTTSQPMMGGLGGGGIGGAG 360
                               ||.:.::|.:.:.... ||  :|.|.:...|
plant   347 ADEENREERRQKVEDDLDIDEDVMKLQQRLNDEEG-SD--TAHHKIDIDQ--------------- 393

  Fly   361 GGISIGGAELKPRFYDESNPSSSTLEGNGGA 391
              :.||..|..|....|:.      .||.||
plant   394 --MRIGSNERAPTIRSEAR------HGNWGA 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	63/125 (50%)
AT5G50020	NP_001190503.1	Cation_efflux	<23..114	CDD:279834	19/79 (24%)
AT5G50020	NP_001190503.1	zf-DHHC	166..291	CDD:279823	64/129 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	154	1.000	Domainoid score	I1348
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	207	1.000	Inparanoid score	I1271
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	1	1.000	-	-		otm2540
orthoMCL	1	0.900	-	-		OOG6_100625
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X394
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830