back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment app and TIP1

DIOPT Version :10

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_197535.2	Gene:	TIP1 / 832157	AraportID:	AT5G20350	Length:	620	Species:	Arabidopsis thaliana

Alignment Length:	337	Identity:	108/337 - (32%)
Similarity:	149/337 - (44%)	Gaps:	62/337 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CDG--------LLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLYFFTMS 89
            |||        .|..||...:..|..:|:. |:::..|.:.|.|...|. |:..:|.:|....:.
plant   263 CDGSSPLGRLSKLGLAPVLWIMILLLLLVY-TNSVVLASNLPKLTTGIG-ALAWLGFILATAGLF 325

  Fly    90 SLLRTTFTDPGVI------PRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKY 148
            ...|.:..|||.|      |:...|:...:  :||    ||:|          .|:.|...:|
plant   326 LFYRCSRKDPGYIRMNIHDPQTMKDDEPLL--KIE----LNNP----------ALLAGNWTQL-- 372

  Fly   149 CFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTH 213
            |.||||.||.||.|||.||.||::||||||||.|||||:|...|:|||: |..||:.| :..||.
plant   373 CATCKIIRPLRAKHCSTCDRCVEQFDHHCPWVSNCVGKKNKWEFFLFLL-LEVLAMLI-TGGVTL 435

  Fly   214 LVLLMK----------KEHEVFNVIKAAPFTVIVVFICFFS--IWSVIGLAGFHTYLTTSDQTTN 266
            ..:|..          ..|...|.:.|..| ::|.|..|||  :.:||..:.....:||::..
plant   436 ARVLSDPSAPSSFGAWMSHVASNHVGALSF-LLVEFCLFFSVAVLTVIQASQISRNITTNEMA-- 497

  Fly   267 EDLKGSFSSKGGPRTQNPYSRGNIC-LNCCHILCGPMTPSLIDRRGIATD--EFIQQMQHQSSPR 328
            ..|:.|:....|.|.:|||..|  | .||...|.......:......||.  |.|..||.|.:|.
plant   498 NALRYSYLRGPGGRFRNPYDLG--CRRNCSDFLVKGYNEDIECHEEDATQRPEGISMMQMQRNPN 560

  Fly   329 ------HALSDV 334
                  |...||
plant   561 LQNGNGHVAIDV 572

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.