DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment app and AT4G24630

DIOPT Version :9

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_194194.2	Gene:	AT4G24630 / 828565	AraportID:	AT4G24630	Length:	407	Species:	Arabidopsis thaliana

Alignment Length:	318	Identity:	114/318 - (35%)
Similarity:	175/318 - (55%)	Gaps:	36/318 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINP-----A 75
            |||.:.|:   |.|||...|.|:..|......||.:||.....||..|....|....:|     |
plant     3 QRVFQVWK---GSNKFILGGRLIFGPDARSLPLTLLLIIVPVVLFCVFVARHLRHEFSPYNAGYA 64

  Fly    76 IPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPP----PRTKE 136
            |.:|..:...:.:..|..|:..|||::||.|:..    |:.:....::::...:.|    |||||
plant    65 IMVVAILFTIYVLILLFFTSARDPGIVPRNSHPP----EEDLRYETTVSADGRQTPSVQIPRTKE 125

  Fly   137 VLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAF 201
            |:|.|.:|::|||.||.::||||.||||:|:|||:||||||||||.|:|.||||:|::|:.|...
plant   126 VIVNGVSVRVKYCDTCMLYRPPRCSHCSICNNCVERFDHHCPWVGQCIGLRNYRYFFMFVSSSTL 190

  Fly   202 LAVFIFSCSVTHLVLLMKKEHE---VFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQ 263
            |.::|||.|..::.:||  :|:   |:..:|.:|:.|:::..||.::|.|.||..||.||.:::|
plant   191 LCIYIFSMSAVYIKILM--DHQQATVWRAMKESPWAVVLMIYCFIALWFVGGLTAFHLYLISTNQ 253

  Fly   264 TTNEDLKGSFSSKGGPRTQNPYSRGNICLNCC-----HILCGPMTPSLIDRRGIATDE 316
            ||.|.|          |.::.:||..:....|     .:.|..:.||..:.|....:|
plant   254 TTYEKL----------RYRSSHSRSIVYNRGCPNNFLEVFCSKVKPSRNNFRAFIEEE 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	62/126 (49%)
AT4G24630	NP_194194.2	zf-DHHC	136..261	CDD:279823	63/136 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	154	1.000	Domainoid score	I1348
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	207	1.000	Inparanoid score	I1271
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	1	1.000	-	-		otm2540
orthoMCL	1	0.900	-	-		OOG6_100625
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X394
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830