DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment app and AT3G56930

DIOPT Version :9

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_191252.1	Gene:	AT3G56930 / 824860	AraportID:	AT3G56930	Length:	477	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	164/571 - (28%)
Similarity:	240/571 - (42%)	Gaps:	166/571 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MAPNQ-RVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLAD--SIN 73
            ||.|: ::.|.::::.|.|||.|.|.|:..|.....||:.|||.|.:.:||......:||  :.|
plant     1 MAWNETKLKRLYQVWRGSNKFLCGGRLIFGPDASSLYLSTILILGPAVMFFVKMYTKMADPRTKN 65

  Fly    74 P--AIPI--VGAVLYFFTMSSLLRTTFTDPGVIPRA----SNDEAAYIEKQIEVPNSLNSPTY-- 128
            |  .|||  |..:|....:..||.|:..|||::||:    ..|:|         |:| .:|:.
plant    66 PNLCIPILCVSWILTILDIFFLLMTSSRDPGIVPRSFRPPETDDA---------PDS-TTPSMEW 120

  Fly   129 ---RPP----PRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGK 186
               |.|    ||.|:|.|.|.|||:|:|.||.::|||||||||:|:|||.||||||||||.|:|.
plant   121 VSGRTPNIRIPRVKDVTVNGHTVKVKFCDTCLLYRPPRASHCSICNNCVQRFDHHCPWVGQCIGV 185

  Fly   187 RNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTV---IVVFICFFSIWSV 248
            ||||||::|:.:...|.:::|:.|  .|.:..:...|..::.||....|   |::..||.::|.|
plant   186 RNYRFFFMFISTSTTLCIYVFAFS--WLNIFQRHMDEKISIWKAISKDVLSDILIVYCFITVWFV 248

  Fly   249 IGLAGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIA 313
            .||..||:||..::|||.|:.:..:..|     :|||::| |..|...|....:.||:...|...
plant   249 GGLTIFHSYLICTNQTTYENFRYRYDKK-----ENPYNKG-ILGNIWEIFLSKIPPSMNKFRSFV 307

  Fly   314 TDEFIQQMQHQSSPRHALSDVLSASHMVTTSQPMMGGLGGGGIGGAGGGISIGGAELKPRFYDES 378
            .:|....|..: :|...|.:.|     |::.:.:...:|||                  |..|||
plant   308 KEEDYMMMMVE-TPTSNLGESL-----VSSKEKIDIEMGGG------------------RIVDES 348

  Fly   379 NPSSSTLEGNGGAINGHGNGHGNGFDHPPPSYDLVQNGKSRKHHQQRCSLQTLLPASAQQQFKAS 443
            ..|.|..|                         :::|          .:.:.|.....:...||.
plant   349 GKSYSLPE-------------------------ILRN----------LNYEDLEDDCEEDDLKAK 378

  Fly   444 KHKHKQLKQHLVAAELQQHEGGPGPGPNSPSLLRSPATSSSYRLNLKRSLHLPLTPSYDDVRHSP 508
            .|.|....||       ||..|..|                           |..|.:
plant   379 DHHHHHHHQH-------QHNEGIIP---------------------------PFDPFF------- 402

  Fly   509 LPLLHHHVHAQQTTAIGTVAAAAAAVASGASGTNTGTGTGTGGSSSSATTT 559
                        |..||             |..:...|..:|||||....|
plant   403 ------------TNEIG-------------SNKDERNGEESGGSSSDGENT 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	59/126 (47%)
AT3G56930	NP_191252.1	DHHC	146..271	CDD:396215	59/126 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	154	1.000	Domainoid score	I1348
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	207	1.000	Inparanoid score	I1271
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	1	1.000	-	-		otm2540
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X394
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930