Protein Alignment app and AT3G22180

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_188857.1
• Gene: AT3G22180 / 821782
• AraportID: AT3G22180
• Length: 706
• Species: Arabidopsis thaliana
• Alignment Length: 825
• Identity: 161/825 - (19%)
• Similarity: 259/825 - (31%)
• Gaps: 304/825 - (36%)

  Fly    50 CILITGTSALFFAFDCPFL--------------------------ADSINPAIPIVGAVL----- 83
            |:|:..    |:||..||:                          ..:||||.|.:.::.
plant    23 CLLVVA----FYAFFAPFVGGRIWEYVLIGVYSPVAILVFVLYVRCTAINPADPRIMSIFDTGVN 83

  Fly    84 -----------YFFTMSSLLRTTFTDPGVIPRAS-----NDEAAYIEKQIEVPNSLNSPTYRP-- 130
                       |..|.|.|.    ..|.|:.|:|     :.....:|....|.:......|.|
plant    84 GDGMVRGLSRNYDETGSQLQ----ASPSVVSRSSTVAGNSSVKGSVEDAQRVESVSRRSCYNPLA 144

  Fly   131 ---------PPRTKE--VLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCV 184
                     ..|.||  ...:|.:.:..:|..|.......:.||..||.|||.|||||.|:.|||
plant   145 VFCYVFVVEDCRKKEGPAEEQGNSEEALFCTLCNCEVRKFSKHCRSCDKCVDCFDHHCKWLNNCV 209

  Fly   185 GKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVI 249
            |::||..|           |.:.|.|:..|            :|:||....::|.:
plant   210 GRKNYVTF-----------VSLMSASLLWL------------IIEAAVGIAVIVRV--------- 242

  Fly   250 GLAGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYSRG------NICLNCCHILCGPMTP---- 304
                |....|...:..|             |..|.:||.      .:|.......|.|:..
plant   243 ----FVNKQTMETEIVN-------------RLGNSFSRAPLAAVVGLCTAVAIFACFPLGELLFF 290

  Fly   305 -SLIDRRGIATDEFIQQMQHQSSPRHALSDVLSASHMVTTSQPMMGGLGGGGIGGAGGGISIGGA 368
             .|:.::||.|.|::..|:       |:|:                         |..|.|: ..
plant   291 HMLLIKKGITTYEYVVAMR-------AMSE-------------------------APDGASV-DE 322

  Fly   369 ELKPRFYDESNPSSSTLEGNGGAINGHGNGHGNGFDH------PPPSYDLVQNGKSRKHHQQRCS 427
            |::...|..:          |.|..|...|...|..:      ||..:|   |......|...|.
plant   323 EIQNVLYSPT----------GSATTGFSGGSSLGLPYRGVWCTPPRVFD---NQDEVIPHLDPCM 374

  Fly   428 LQTLLPASAQQQFKASKHKHKQLKQHLVAAELQQHEGGPGPGPNSPSLLRSPATSSSYRLNLKRS 492
            :.:.:...|....|.:|...:.:|::  |.:|.:.:    |...:.:..|:.|:||..|
plant   375 VPSTVDPDAPGSEKGTKALKRPVKRN--AWKLAKLD----PNEAARAAARARASSSVLR------ 427

  Fly   493 LHLPLTPSYDDVRHSPLPLLHHHVHAQQTTAIGTVA-----------AAAAAVASG--------- 537
                             |:.:.|:.....::||||:           ||:..:.:.
plant   428 -----------------PIDNRHLPDNDLSSIGTVSIISSVSTDANVAASKEIRNNDLRSSLSRN 475

  Fly   538 ----ASGTNTGTGTGTGGSSSSATTTAPTSVSVSLATAPPPLAPRRPSTLQLQASGAISASNSTL 598
                :.|:.....||:.|.|:   .::|:.|..|:..||.|..|            .|..:..|.
plant   476 SFAPSQGSRDEYDTGSHGMSN---LSSPSHVHESVTLAPLPQNP------------TIVGNRFTA 525

  Fly   599 TT--IHTTAPQ---------------APA---------------PTDFKYYSPQRSTDSNLMRNY 631
            |:  :|:|...               |||               |...:|.|...:|.|. :||.
plant   526 TSHHMHSTFDDKVLHRGNDADPLFLFAPATSHLRDVRKTSVVWDPEAGRYVSAPVTTTSE-VRNR 589

  Fly   632 PFPKAARGMRRQSTMSV----DSQKVNIAGYQPLPM-----RKPYKHQEVMFELKSPTNRLTIRE 687
            ....:::....|:...:    ||...:.|...|||:     |..|....:.:  ..|...:..|:
plant   590 LLNPSSQTASTQNPRPILPAHDSSSGSSALRDPLPLHQAERRLTYTGDSIFY--GGPLINIPTRD 652

  Fly   688 CDFGGGGEPCDDDQSIKDSQIFRVSKRNLYMNHRSPWKERDRYSN 732
            ....|.|       .::|     |..|.....||.....||..||
plant   653 TPRSGRG-------LVRD-----VQDRLASTVHRDARIRRDSTSN 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	33/123 (27%)
AT3G22180	NP_188857.1	DHHC	168..305	CDD:396215	45/185 (24%)