Protein Alignment app and ZDHHC14

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_016866796.1
• Gene: ZDHHC14 / 79683
• HGNCID: 20341
• Length: 506
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 195/441 - (44%)
• Similarity: 250/441 - (56%)
• Gaps: 93/441 - (21%)

  Fly    65 CPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYR 129
            ||:||..|.||||.|..:|:||.|.:||||:|:||||:|||:.||||.:|:||::.|..:|..||
Human   101 CPYLAVKITPAIPAVAGILFFFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYR 165

  Fly   130 PPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYL 194
            ||||||||::.||||||||||||||||||||||||||||||:||||||||||||||||||||||:
Human   166 PPPRTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYM 230

  Fly   195 FLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLT 259
            |::||:||.||||:..:|| |:|..::....|.:|.:|.:|:...:||||:||::||:||||||.
Human   231 FILSLSFLTVFIFAFVITH-VILRSQQTGFLNALKDSPASVLEAVVCFFSVWSIVGLSGFHTYLI 294

  Fly   260 TSDQTTNEDLKGSFSSKGGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQ 324
            :|:||||||:|||:|:|.|....||||.|||..|||..||||::||||||||     :||.
Human   295 SSNQTTNEDIKGSWSNKRGKENYNPYSYGNIFTNCCVALCGPISPSLIDRRG-----YIQP---- 350

  Fly   325 SSPRHALSDVLSASHMVTTSQPMMGGLGGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNG 389
                             .|.||          .....||::.||
Human   351 -----------------DTPQP----------AAPSNGITMYGA--------------------- 367

  Fly   390 GAINGHGNGHGNGFDHPPPSYDLVQNGKSRKHHQQRC--SLQTLLPASAQQQFKASKHKHKQLKQ 452
                                    ...:|....|.:|  |.:.:|.|:|....        |.:.
Human   368 ------------------------TQSQSDMCDQDQCIQSTKFVLQAAATPLL--------QSEP 400

  Fly   453 HLVAAELQQHEGGPGPGPNSPSLLRSPATSSSYRLNLKRSLHLPLTPSYDD 503
            .|.:.||.. .|.||.|....||...|.|..:...||..:....:.|..|:
Human   401 SLTSDELHL-PGKPGLGTPCASLTLGPPTPPASMPNLAEATLADVMPRKDE 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	85/123 (69%)
ZDHHC14	XP_016866796.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151633
Domainoid	1	1.000	206	1.000	Domainoid score	I2911
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H62301
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	1	1.000	-	-		otm42161
orthoMCL	1	0.900	-	-		OOG6_100625
Panther	1	1.100	-	-	LDO	PTHR22883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R405
SonicParanoid	1	1.000	-	-		X394
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.740