DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment app and Zdhhc20

DIOPT Version :9

Sequence 1:NP_648561.2 Gene:app / 39399 FlyBaseID:FBgn0260941 Length:755 Species:Drosophila melanogaster
Sequence 2:XP_006519721.1 Gene:Zdhhc20 / 75965 MGIID:1923215 Length:475 Species:Mus musculus


Alignment Length:293 Identity:84/293 - (28%)
Similarity:125/293 - (42%) Gaps:50/293 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 NMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPA 75
            ||||       |.|:.     .|..::...|   |.::|.:::..    ::|:.......:|:..
Mouse    95 NMAP-------WTLWR-----CCQRVVGWVP---VLFITFVVVWS----YYAYVVELCVSTISRT 140

  Fly    76 IPIVGAVLY------FFTMS--SLLRTTFTDPGVIPR---ASNDEAAYIEKQIEVPNSLNSPTYR 129
            ......|:|      ||.|.  |...|.||.|....:   .||.|....||  |..........|
Mouse   141 GEKGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEK--EFSQERQQDILR 203

  Fly   130 PPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYL 194
            ...|...:.....:..::||..|::.:|.||.|||.||.||.:.|||||||.||||..||:||.|
Mouse   204 RAARDLPIYTTSASKAIRYCEKCQLIKPDRAHHCSACDRCVLKMDHHCPWVNNCVGFTNYKFFML 268

  Fly   195 FLVSLAFLAVFIFSCSVTHLV----LLMKKEHEVFNVIKAAPFTVI--------VVFICFFSIW- 246
            ||:......:|:.:..:.:.:    |..:|..|  |..|..| ||:        |:|:.|.|.. 
Mouse   269 FLLYSLLYCLFVAATVLEYFIKFWTLCRRKSTE--NCPKNEP-TVLNFPSAKFHVLFLFFVSAMF 330

  Fly   247 --SVIGLAGFHTYLTTSDQTTNEDLKGSFSSKG 277
              ||:.|..:|.:|...::||.|..:....|.|
Mouse   331 FVSVLSLFSYHCWLVGKNRTTIESFRAPMFSYG 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
appNP_648561.2 zf-DHHC 146..270 CDD:279823 52/138 (38%)
Zdhhc20XP_006519721.1 DHHC 111..411 CDD:388695 77/265 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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