Protein Alignment app and zdhhc5

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001037950.1
• Gene: zdhhc5 / 733708
• XenbaseID: XB-GENE-5962635
• Length: 571
• Species: Xenopus tropicalis
• Alignment Length: 699
• Identity: 183/699 - (26%)
• Similarity: 264/699 - (37%)
• Gaps: 252/699 - (36%)

  Fly     8 CCSNMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVF----YL----TCILITGTSALFFAFD 64
            ||:::.|....|                  |.|.:...|    |:    ..:.:.|::.|||.|.
 Frog     4 CCTSLTPLYIFT------------------MPAENVKSFKPSKYVPVAAATVFLVGSTTLFFIFT 50

  Fly    65 CPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYR 129
            |.:|:..::.|:|...||::.|.:::....||.|||:.|||..||    :|:    :...:|.|
 Frog    51 CAWLSVEVSFALPAYNAVMFLFVLANFSMATFMDPGIFPRAEEDE----DKE----DDFRAPLY- 106

  Fly   130 PPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYL 194
                 |.|.|:|..|::|:|.||:.:||||.||||:|||||:.||||||||.||:|:||||:|:|
 Frog   107 -----KTVEVRGVQVRMKWCSTCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFL 166

  Fly   195 FLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLT 259
            |||||....:.:|.|.   |...|....::.::..|...:|:.|...||  :.|.||.|||..|.
 Frog   167 FLVSLTLHIISVFICG---LFYTMGHPDQLGDIPAAVTISVLCVAGLFF--FPVAGLTGFHIVLV 226

  Fly   260 TSDQTTNEDLKGSFSSKGGPRTQNPYSRGNICLNCCHILCGPMTPSLID---------------- 308
            ...:||||.:.|.|  :||   .||:|.| .|.|..|:||....|..:.
 Frog   227 FRGRTTNEQVTGKF--RGG---VNPFSDG-CCQNVSHVLCSSTPPRYLKSSQPLLHVSPPFLHPV 285

  Fly   309 -----------RRGIATDEFIQQMQHQSS----------------PRHALSDVLS-ASHMVTTSQ 345
                       ..|:.:..  |..|.|||                |:..||.... ..|:.||.:
 Frog   286 ISENQIGLKILENGVQSPS--QHYQSQSSLELTESQSADADPPPPPKPVLSHFTGLRGHLNTTEK 348

  Fly   346 --------------PMM----GGLGGGGIGGAGGGI---------SIGGAELKPRFYDESNPSSS 383
                          |.|    .|..||.:..||..:         ||..:||       |.||||
 Frog   349 EVENAFSATESAPTPTMYRYRPGYSGGSVPQAGTKLARVDSLQDSSIPTSEL-------SRPSSS 406

  Fly   384 TLEGNGGAINGHGNGHGNGFDHPPPSYDLVQNGKSRKHHQQRCSLQTLLPASAQQQFKASKHKHK 448
            ..|                     ||.|     ...:|          |||.
 Frog   407 RSE---------------------PSLD-----PDPEH----------LPAR------------- 422

  Fly   449 QLKQHLVAAELQQHEGGPGPGPNSPSLLRSPATSSSYRLNLKRSLHLPLTPSYDDVRHSPLPLLH 513
                   ::.|:...|.|||.|:.||   ...||:||:             |::..::..|
 Frog   423 -------SSSLRSAVGIPGPLPSLPS---EGTTSTSYK-------------SFNQTQNGSL---- 460

  Fly   514 HHVHAQQTTAIGTVAAAAAAVASGASGTNTGTGTGTGGSSSSATTTAPTSVSVSLATAPPPLAPR 578
                            :..::.|.:..|:..|...:....|:.....|        ..|||:|||
 Frog   461 ----------------SYQSLLSPSDETDPETAGYSSPYLSARERPRP--------ACPPPIAPR 501

  Fly   579 ---------RP-----STLQL-------QASGAISASNSTLTTIHTTAP 606
                     ||     :||.|       ......|.|||..|...:.:|
 Frog   502 YGKPRISNYRPGDADAATLPLLTLRDESPVKSTHSCSNSQTTVSPSVSP 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	59/123 (48%)
zdhhc5	NP_001037950.1	zf-DHHC	117..239	CDD:279823	59/126 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3618
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.060