back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment app and Zdhhc2

DIOPT Version :10

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_848482.1	Gene:	Zdhhc2 / 70546	MGIID:	1923452	Length:	366	Species:	Mus musculus

Alignment Length:	349	Identity:	89/349 - (25%)
Similarity:	142/349 - (40%)	Gaps:	61/349 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LITGTSALFFAFD-CPFLADSINPAIPIVGAVLYFFTMS--SLLRTTFTDPGVIPRASNDE--AA 111
            |:.|.|...:|.. |....::|...:..:.|....|.|.  |..:|.||    :|...:.|  .:
Mouse    27 LLLGWSYYAYAIQLCIVSMENIGEQVVCLMAYHLLFAMFVWSYWKTIFT----LPMNPSKEFHLS 87

  Fly   112 YIEKQI---EVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRF 173
            |.||::   |.....:....|...:...:..:..:..::||..|::.:|.|..|||:||.|:.:.
Mouse    88 YAEKELLEREPRGEAHQEVLRRAAKDLPIYTRTMSGAIRYCDRCQLIKPDRCHHCSVCDKCILKM 152

  Fly   174 DHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLL--------MKKEHEVFNVIKA 230
            |||||||.||||..||:||.|||.......:||.:..:.:.:..        ..|.|.:|....|
Mouse   153 DHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQYFIRFWTNGLPDTQAKFHIMFLFFAA 217

  Fly   231 APFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDL----------KGSFS---SKGGPRT- 281
            |.|:|           |:..|.|:|.:|.:.:::|.|..          |..||   ||...:.
Mouse   218 AMFSV-----------SLSSLFGYHCWLVSKNKSTLEAFRNPVFRHGTDKNGFSLGFSKNMRQVF 271

  Fly   282 --QNPY-------SRGNIC-LNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLS 336
              :..|       |:|:.| ...|.:...|..||    .....:..::..::...|...|.:  |
Mouse   272 GDEKKYWLLPVFSSQGDGCSFPTCLVNQDPEQPS----TPAGLNSTVKNPENHQFPAKPLRE--S 330

  Fly   337 ASHMVTTSQPMMGGLGGGGIGGAG 360
            .||::..||.........|.|.||
Mouse   331 QSHLLKDSQTWTESSANPGKGKAG 354

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.