Protein Alignment app and Zdhhc25

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_081582.1
• Gene: Zdhhc25 / 70073
• MGIID: 1917323
• Length: 279
• Species: Mus musculus
• Alignment Length: 311
• Identity: 84/311 - (27%)
• Similarity: 127/311 - (40%)
• Gaps: 103/311 - (33%)

  Fly    13 APNQRVTRKWELFAGRNKFYCD--GLL--MSAPHTGVFYLTCILITGTSALFFAFDCPFLADSIN 73
            |||||.   |        |..|  |:|  |:|        ..::::|...||.....|     .|
Mouse    23 APNQRC---W--------FILDPIGILCAMAA--------WALVLSGGWVLFRDLLIP-----SN 63

  Fly    74 PAIPIVGAVLYFFTMSSL-----LRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPR 133
            ..:.||...:.|..::||     |||..||||.:|                   |.:|   |.|.
Mouse    64 NMLYIVANGVVFHLLASLALASHLRTMLTDPGSVP-------------------LGNP---PGPD 106

  Fly   134 TKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVS 198
            |           :.||..|....|..|.||::|..|:.:.||||||:.||:|:.|.::|.||.:.
Mouse   107 T-----------VSYCTDCHSAIPRTACHCTVCQRCIRKNDHHCPWINNCIGEDNQKYFLLFTMY 160

  Fly   199 LAFLAVFIFSCSVTHLVLL---------MKKEHEVFNVIK-AAP--FTVIVVFICFFSIWSVIGL 251
            :...:        ||::||         |:.|.:..:.:. .||  |.::|..:.|  :::|:.|
Mouse   161 IGLTS--------THVLLLLGIPVLCSYMRGEWDSSSTVSLPAPILFLLLVAIMGF--LFAVVML 215

  Fly   252 AGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYSRG--NICLNCCHILCG 300
            .. ...:..||:||.|.|           .||.:|.|  :.|.| ...:||
Mouse   216 CS-QMCVIYSDKTTTELL-----------YQNTHSGGRWSKCAN-MKAVCG 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	40/135 (30%)
Zdhhc25	NP_081582.1	DHHC	110..230	CDD:396215	39/130 (30%)