Protein Alignment app and Zdhhc12

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_079704.2
• Gene: Zdhhc12 / 66220
• MGIID: 1913470
• Length: 281
• Species: Mus musculus
• Alignment Length: 287
• Identity: 76/287 - (26%)
• Similarity: 117/287 - (40%)
• Gaps: 49/287 - (17%)

  Fly    35 GLLMSAPHTGVFYLTCILITGTSALFFAFD------CPFLADSINP----------AIPIVGAVL 83
            |:|:...||       :|..|.:.:.|..|      .|..|..|..          .:|:...:|
Mouse    10 GMLVRTGHT-------VLTWGITLVLFLHDTGEPDTAPPRAHPITQLRQWEEQGELLLPLTFLLL 67

  Fly    84 YFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKY 148
            ...::...|..:..|||           |:..|         |..:..|:.::..:..|.|.|:.
Mouse    68 VLSSLLLYLAVSLMDPG-----------YVTTQ---------PQPQGEPKEEQAAMVPQAVPLRR 112

  Fly   149 CFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTH 213
            |..|.:.:|.||.||..|..||.|:||||||:.||||:||:..|..:|.  ..|.|.::...:..
Mouse   113 CRHCLVLQPLRARHCRDCRRCVRRYDHHCPWMENCVGERNHPLFVAYLA--LQLVVLLWGLCLAW 175

  Fly   214 LVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGG 278
            ..|...:...::.......||..:: :.||::...:.||. |.||...:.||.|.:.....:...
Mouse   176 SGLQFFQPWGLWLRSTGLLFTTFLL-LSFFALVVALLLAS-HLYLVARNTTTWEFISSHRIAYLR 238

  Fly   279 PRTQNPYSRGNICLNCCHILCG-PMTP 304
            .||.||:.||. ..|..|..|| |..|
Mouse   239 QRTSNPFDRGP-TRNLAHFFCGWPSGP 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	41/123 (33%)
Zdhhc12	NP_079704.2	DHHC	<137..231	CDD:396215	29/97 (30%)