Protein Alignment app and ZDHHC6

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001338011.1
• Gene: ZDHHC6 / 64429
• HGNCID: 19160
• Length: 413
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 71/266 - (26%)
• Similarity: 94/266 - (35%)
• Gaps: 108/266 - (40%)

  Fly     9 CSNMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSIN 73
            ||.||....|...|.|                 ||          ||.|..|...        ||
Human    34 CSTMAMIDSVLWYWPL-----------------HT----------TGGSVNFIML--------IN 63

  Fly    74 PAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVL 138
            ..:.|:  ..||..|       |..||.:|.....|
Human    64 WTVMIL--YNYFNAM-------FVGPGFVPLGWKPE----------------------------- 90

  Fly   139 VKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFL- 202
            :...|:.|:||..|:.::.||:.||..|:.||.:.||||||:.||.|.:|:..|.|||: ||.|
Human    91 ISQDTMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGYQNHASFTLFLL-LAPLG 154

  Fly   203 ---AVFIFSCSVTHLVLLMKKE--HEV---FNVIK----AA---PFTVIVVFICFFSIWSVIGLA 252
               |.|||       |:.|..:  |.:   :|.:|    ||   |..::           ..|||
Human   155 CIHAAFIF-------VMTMYTQLYHRLSFGWNTVKIDMSAARRDPLPIV-----------PFGLA 201

  Fly   253 GFHTYL 258
            .|.|.|
Human   202 AFATTL 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	46/129 (36%)
ZDHHC6	NP_001338011.1	DHHC	95..241	CDD:396215	47/132 (36%)
		SH3	317..394	CDD:418401
		Di-lysine motif. /evidence=ECO:0000269|PubMed:21926431	410..413

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810