DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment app and zdhhc18a

DIOPT Version :9

Sequence 1:	NP_648561.2	Gene:	app / 39399	FlyBaseID:	FBgn0260941	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_001071031.1	Gene:	zdhhc18a / 564062	ZFINID:	ZDB-GENE-060929-424	Length:	467	Species:	Danio rerio

Alignment Length:	302	Identity:	190/302 - (62%)
Similarity:	230/302 - (76%)	Gaps:	3/302 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 NQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIV 79
            :||:.||||:|.|:|:|||||.:|.|...||..||..||..||.|||.||||||.|.:...||::
Zfish    32 SQRLRRKWEVFPGKNRFYCDGRIMLARQCGVLPLTIGLIFITSVLFFTFDCPFLVDHLTVFIPVI 96

  Fly    80 GAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTV 144
            |.||:.|.:.|||:|:|||||::|||..||||.|||||:  || .|.||||||||||:|:..|.|
Zfish    97 GGVLFIFVVISLLQTSFTDPGILPRALPDEAADIEKQID--NS-GSSTYRPPPRTKEILINDQVV 158

  Fly   145 KLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSC 209
            ||||||||::|||||.||||||||||:||||||||||||||||||||||.|:|||:||..|||.|
Zfish   159 KLKYCFTCRMFRPPRTSHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYAFIVSLSFLTSFIFGC 223

  Fly   210 SVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFS 274
            .:|||.|..:..:.....|:.:|.:|:.:.||||||||::||:||||||..|:.|||||:|||:|
Zfish   224 VITHLTLRSQGGNGFIQAIQDSPASVVELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWS 288

  Fly   275 SKGGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDE 316
            ||.|..:.|||:..||..|||.:|||||.||||||||....|
Zfish   289 SKRGEESGNPYTYNNIFTNCCVVLCGPMPPSLIDRRGFVPPE 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	83/123 (67%)
zdhhc18a	NP_001071031.1	zf-DHHC	160..284	CDD:279823	83/123 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	202	1.000	Domainoid score	I2943
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	1	1.000	-	-		otm25516
orthoMCL	1	0.900	-	-		OOG6_100625
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X394
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.880