Protein Alignment app and ZDHHC7

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001139020.1
• Gene: ZDHHC7 / 55625
• HGNCID: 18459
• Length: 345
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 86/331 - (25%)
• Similarity: 134/331 - (40%)
• Gaps: 102/331 - (30%)

  Fly     5 CCCCCSNMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFA------F 63
            |...|:.|.        |.|.|     |.|           |.:|.:::..:...:::      |
Human    46 CGMICAVMT--------WLLVA-----YAD-----------FVVTFVMLLPSKDFWYSVVNGVIF 86

  Fly    64 DCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASND---EAAYIEKQI-------- 117
            :|                 |....:||.|||..||    |..|:|   .|..::..:
Human    87 NC-----------------LAVLALSSHLRTMLTD----PEKSSDCRPSACTVKTGLDPTLVGIC 130

  Fly   118 -EVPNSLNSPTYRPPPR---TKEVLVKGQTVKLK------YCFTCKIFRPPRASHCSLCDNCVDR 172
             |...|:.|......|:   |||.:   ::::||      .|..|...:|.||.|||:|..|:.:
Human   131 GEGTESVQSLLLGAVPKGNATKEYM---ESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRK 192

  Fly   173 FDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVF-IFSCSVTHLVLLMKKEHEVFNVIKAAPFTVI 236
            .|||||||.||||::|.|||.||.:.:|..:|. :..|....:..:..:..|..:.  :.|.|||
Human   193 MDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGFQFISCVRGQWTECSDF--SPPITVI 255

  Fly   237 -VVFIC-----FFSIWSVIGLAGFHTYLTTSDQTTNEDLK-------------GSFSSKGGPRT- 281
             ::|:|     ||:..:|  :.|...:...:|:|..|.||             |..|..|||.:
Human   256 LLIFLCLEGLLFFTFTAV--MFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSL 318

  Fly   282 --QNPY 285
              .||:
Human   319 LWMNPF 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	46/136 (34%)
ZDHHC7	NP_001139020.1	zf-DHHC	168..295	CDD:307600	46/130 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810