Protein Alignment app and zdhhc8a

DIOPT Version :9

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_683670.3
• Gene: zdhhc8a / 555918
• ZFINID: ZDB-GENE-091118-26
• Length: 622
• Species: Danio rerio
• Alignment Length: 642
• Identity: 173/642 - (26%)
• Similarity: 256/642 - (39%)
• Gaps: 164/642 - (25%)

  Fly    52 LITGTSALFFAFDCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQ 116
            ::..:|.|||.|.||:||.|::||.|....||:.|.|::....||.|.||.|||:.||
Zfish    16 ILVSSSTLFFVFTCPWLAVSVSPAFPPCVGVLFLFVMANFTMATFMDAGVFPRANEDE------- 73

  Fly   117 IEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVG 181
             :..:...:|.|    :|.|  |:|..|::|:|.:|..:||||.||||:||:||:.||||||||.
Zfish    74 -DKDDDFRAPLY----KTAE--VRGVQVRMKWCGSCHFYRPPRCSHCSVCDHCVEDFDHHCPWVN 131

  Fly   182 NCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIW 246
            ||:|:||||||:|||::|:...|.:||.:   |:.::.....::....|....|:.|...||.
Zfish   132 NCIGRRNYRFFFLFLLTLSLHMVGVFSGA---LLFVLDHLENLWEPHAAVSLAVMSVSGLFFI-- 191

  Fly   247 SVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYSRGNICLNCCHILCGPMTP----SLI 307
            .|:||:.||..|....:||||.:.|.|  :||   .||::|| .|.|...:|..|:||    .:.
Zfish   192 PVLGLSCFHLVLVARGRTTNEQVTGKF--QGG---VNPFTRG-CCQNLQFLLFSPVTPRYTGKVS 250

  Fly   308 DRRGIATDEFIQQMQHQSSPRHALSDVLSASHMVTTSQPMMGGLGGGGIGGAGGGISIGGAELKP 372
            ||..:.    ||...||..| |.|:.|.|                        ...||....|..
Zfish   251 DRLAVC----IQPPFHQPEP-HDLTPVKS------------------------NDSSIQSQTLTL 286

  Fly   373 RFYDE-SNPSSSTLEGNGGAINGHGNGHGNGFDHPPPSYDLVQNGKSRKHHQQRCSLQTLLPASA 436
            :..|| .:|.|..|                  ..|||                       ||
Zfish   287 KCLDEDEDPDSKRL------------------TTPPP-----------------------LP--- 307

  Fly   437 QQQFKASKHKHKQLKQHLVAAE---LQQHEGGPGPGPNSPSLLRSPATSSSYRLNLKRSLHLPLT 498
                  .|.....|:.||...|   ||.....|.....||.......|...|:|. :..:.:.::
Zfish   308 ------PKPDPVLLRNHLAVLEESLLQSRALLPSGHNMSPLQSSESPTKELYQLT-RDQMGMRIS 365

  Fly   499 PSYDDVRHSPLPLLH--HHVHAQQTTAIGTVAAAAAAVASGASGTNTGTGTGTGGSSSSATTTAP 561
            |.......|...||.  :|:..|...::...:.:.:...|...|            |..|.|.||
Zfish   366 PLLSQEHASEPSLLQSDNHMSLQPINSLTLNSCSLSLKHSARRG------------SQRAETQAP 418

  Fly   562 TSVSVSLATAPPPLAPR----------RPSTLQLQ--------ASGAISASNSTLTTIHTTAPQA 608
            .::     ..|..|:.|          ||:..|:|        :.|.:...:....|..:...:.
Zfish   419 QTI-----PTPSALSSRSGSLSYDSLLRPAGHQMQFRPTDTNLSRGPVRTCSPVFLTGQSPQHRE 478

  Fly   609 PAPTDFKYYSPQRSTDSNLMRNYPFPKAARGMRRQSTMSVDSQKVNIAGYQPLPMRK 665
            |:|..:         ||     .|.|..:....|:......|...:.:|...:|.|:
Zfish   479 PSPVCY---------DS-----LPKPVMSSIQERREPEDKHSSTADASGIYDVPSRR 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	55/123 (45%)
zdhhc8a	XP_683670.3	zf-DHHC	95..217	CDD:279823	55/126 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010