Protein Alignment app and ZDHHC3

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_047304216.1
• Gene: ZDHHC3 / 51304
• HGNCID: 18470
• Length: 412
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 74/310 - (23%)
• Similarity: 124/310 - (40%)
• Gaps: 79/310 - (25%)

  Fly    48 LTCILITGTSALFFAFDCPF--LADSINPAIPIVGAVLY----FFTMSSLLRTTFTDPGVIPRAS 106
            :.|.::|....|:..|...|  |..|.:....|:..:::    |..::|..|...|||   .|..
Human    45 IACAIVTWFLVLYAEFVVLFVMLIPSRDYVYSIINGIVFNLLAFLALASHCRAMLTDP---VRTC 106

  Fly   107 NDEA-AYIEKQIEVPNSLNSPT-------YRPPPR---TKEVLVKGQTVKLK------YCFTCKI 154
            .:.| ..:.:....|..|:.|.       ....|:   |||.:   ::::||      .|..|..
Human   107 TEMAFTLLGRGASFPEKLDKPVSGRSKCLLGAVPKGNATKEFI---ESLQLKPGQVVYKCPKCCS 168

  Fly   155 FRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMK 219
            .:|.||.|||:|..|:.:.|||||||.||||:.|.::|.||.:.:|.:::........|.:...:
Human   169 IKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFE 233

  Fly   220 KE------------------HEVFNVIK---------AAPFTVI-VVFICF----FSIWSVIGLA 252
            ::                  ||....:.         :.|.||| ::.:||    |.|::.: :.
Human   234 EDWTTYGLNREEMAETGISLHEKMQPLNFSSTECSSFSPPTTVILLILLCFEGLLFLIFTSV-MF 297

  Fly   253 GFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYSR-GNICLNCCHILCGP 301
            |...:...:|:|...            |.|.|..| ..:|..|    |||
Human   298 GTQVHSICTDETKRW------------RKQCPQWRVKGLCAGC----CGP 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	42/161 (26%)
ZDHHC3	XP_047304216.1	DHHC	162..309	CDD:396215	39/147 (27%)