Protein Alignment app and ZDHHC9

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_057116.2
• Gene: ZDHHC9 / 51114
• HGNCID: 18475
• Length: 364
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 184/344 - (53%)
• Similarity: 239/344 - (69%)
• Gaps: 14/344 - (4%)

  Fly    10 SNMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINP 74
            |.|...::||||||...|||.|.|||.:|.|...|:||||..||.||..|||||:|.:||..::|
Human     2 SVMVVRKKVTRKWEKLPGRNTFCCDGRVMMARQKGIFYLTLFLILGTCTLFFAFECRYLAVQLSP 66

  Fly    75 AIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLV 139
            |||:..|:|:.|:|::||||:|:||||||||..||||:||.:||..|.......|||||.|...:
Human    67 AIPVFAAMLFLFSMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGAVPQGQRPPPRIKNFQI 131

  Fly   140 KGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAV 204
            ..|.||||||:||||||||||||||:|||||:|||||||||||||||||||:||||::||:.|.:
Human   132 NNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFILSLSLLTI 196

  Fly   205 FIFSCSVTHLVLLMKKEHEV--FNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNE 267
            ::|:.::.::.|   |..::  ...:|..|.||:.|.||||::|||:||.||||:|...:|||||
Human   197 YVFAFNIVYVAL---KSLKIGFLETLKETPGTVLEVLICFFTLWSVVGLTGFHTFLVALNQTTNE 258

  Fly   268 DLKGSFSSKGGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALS 332
            |:|||::.|.  |.|||||.|||..|||.:||||:.||::|||||...|  :......|.:...|
Human   259 DIKGSWTGKN--RVQNPYSHGNIVKNCCEVLCGPLPPSVLDRRGILPLE--ESGSRPPSTQETSS 319

  Fly   333 DVLSAS-----HMVTTSQP 346
            .:|..|     |:.:...|
Human   320 SLLPQSPAPTEHLNSNEMP 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	77/125 (62%)
ZDHHC9	NP_057116.2	DHHC	138..261	CDD:396215	77/125 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..364		7/38 (18%)