Protein Alignment app and Zdhhc18

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_006539081.1
• Gene: Zdhhc18 / 503610
• MGIID: 3527792
• Length: 407
• Species: Mus musculus
• Alignment Length: 366
• Identity: 200/366 - (54%)
• Similarity: 251/366 - (68%)
• Gaps: 44/366 - (12%)

  Fly    16 QRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVG 80
            :|..||||:|.|||:|||.|.||.|.|.|||.||.:||..|:.|||.||||:||.::..||||:.
Mouse    56 RRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILSTTILFFVFDCPYLARTLTLAIPIIA 120

  Fly    81 AVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVK 145
            |:|:||.||.||:|:|||||::|||:..|||.:||||:   :..|.||||||||:||::.|||||
Mouse   121 AILFFFVMSCLLQTSFTDPGILPRATICEAAALEKQID---NTGSSTYRPPPRTREVMINGQTVK 182

  Fly   146 LKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCS 210
            ||||||||:|||||.||||:|||||:||||||||||||||:|||||||.|::||:||..|||:|.
Mouse   183 LKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACV 247

  Fly   211 VTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSS 275
            ||||.||.:..: ..:.:|..|.:|:.:.||||||||::||:||||||..|:.|||||:|||:||
Mouse   248 VTHLTLLSQGSN-FLSALKKTPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSS 311

  Fly   276 K-GGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLSASH 339
            | ||..:.||||..:|..|||.:||||:.||||||||     |:|......||
Mouse   312 KRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRG-----FVQSDTALPSP------------ 359

  Fly   340 MVTTSQPMMGG---------------------LGGGGIGGA 359
             :.:..|..|.                     |...|:|||
Mouse   360 -IRSDDPACGAKPDASMSVRGLKELLRTATLCLFRSGLGGA 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	83/123 (67%)
Zdhhc18	XP_006539081.1	DHHC	183..306	CDD:396215	83/123 (67%)