Protein Alignment app and Zdhhc14

DIOPT Version :10

• Sequence 1: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001034432.1
• Gene: Zdhhc14 / 499014
• RGDID: 1565877
• Length: 489
• Species: Rattus norvegicus
• Alignment Length: 516
• Identity: 233/516 - (45%)
• Similarity: 296/516 - (57%)
• Gaps: 115/516 - (22%)

  Fly    20 RKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLY 84
            ||||:|.|||||:|:|.:|.|..|||||||.|||..||.|||||||.:||:.|.||||:||.:|:
  Rat    38 RKWEVFPGRNKFFCNGRIMMARQTGVFYLTLILILVTSGLFFAFDCRYLAEKITPAIPVVGGILF 102

  Fly    85 FFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYC 149
            ||.|.:||||:|:||||:|||:.||||.:|:||::.|..:|..||||||||||::.|||||||||
  Rat   103 FFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPRTKEVIINGQTVKLKYC 167

  Fly   150 FTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHL 214
            |||||||||||||||||||||::|||||||||||||||||||||:|::||:||.||||:..:||
  Rat   168 FTCKIFRPPRASHCSLCDNCVEQFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITH- 231

  Fly   215 VLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGP 279
            |:...::....:.:|.:|.:|:...|||||:||:|||:||||||.:|:||||||:|||:|:|.|.
  Rat   232 VIHRSQQKGFLDALKDSPASVLEAVICFFSVWSIIGLSGFHTYLISSNQTTNEDIKGSWSNKRGK 296

  Fly   280 RTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLSASHMVTTS 344
            ...||||.|||..|||..||||::||||||||     :||.                     .|.
  Rat   297 ENYNPYSYGNIFTNCCVALCGPISPSLIDRRG-----YIQP---------------------DTP 335

  Fly   345 QPMMGGLGGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAINGHGNGHGNGFDHPPPS 409
            ||          .....||::.||
  Rat   336 QP----------AAPSNGITMYGA----------------------------------------- 349

  Fly   410 YDLVQNGKSRKHHQQRC--SLQTLLPASAQQQFKASKHKHKQLKQHLVAAELQQHEGGPGPG--- 469
                ...:|....|.:|  |.:.:|.|:|....        |.:..|.:.||.. .|.||.|
  Rat   350 ----TQSQSDMCDQDQCIQSTKFVLQAAATPLL--------QSEPSLTSEELHM-PGKPGLGTPC 401

  Fly   470 -------PNSPSLLRSPATSSSYR----LNLKRSLHLPLTPSYDDVRHSP------LPLLH 513
                   |..||.:.:.||.::..    |..:...|..|||  |:....|      .||.|
  Rat   402 ASLTLGQPTPPSSMPNLATEATLSDIMPLKDEHGGHQFLTP--DEAPSPPRMLGAGSPLAH 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
app	NP_648561.2	DHHC	146..270	CDD:396215	84/123 (68%)
Zdhhc14	NP_001034432.1	DHHC	164..287	CDD:396215	84/123 (68%)
		Atrophin-1	351..>461	CDD:460830	30/121 (25%)